Megovalicin G

Details

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Internal ID a4969c7a-e70d-4493-a41f-94486df6c1a3
Taxonomy Phenylpropanoids and polyketides > Macrolide lactams
IUPAC Name (2S,6S,8S,9R,12Z,14E,25R,26E)-16-ethyl-6,8,9-trihydroxy-12-(methoxymethyl)-25,27-dimethyl-2-propyl-1-oxa-4-azacyclooctacosa-12,14,26-triene-3,28-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C35H61NO7/c1-6-15-33-34(40)36-24-30(37)23-32(39)31(38)21-20-29(25-42-5)19-14-18-28(7-2)17-13-11-9-8-10-12-16-26(3)22-27(4)35(41)43-33/h14,18-19,22,26,28,30-33,37-39H,6-13,15-17,20-21,23-25H2,1-5H3,(H,36,40)/b18-14+,27-22+,29-19-/t26-,28?,30+,31-,32+,33+/m1/s1
InChI Key KPPGZMXMBMURID-UVLJCXNLSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C35H61NO7
Molecular Weight 607.90 g/mol
Exact Mass 607.44480328 g/mol
Topological Polar Surface Area (TPSA) 125.00 Ų
XlogP 7.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Megovalicin G

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.45% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 97.96% 97.09%
CHEMBL2581 P07339 Cathepsin D 97.29% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 94.46% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 92.76% 99.23%
CHEMBL3359 P21462 Formyl peptide receptor 1 91.23% 93.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.37% 86.33%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 87.57% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.49% 95.56%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 86.14% 92.62%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 86.01% 85.14%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.25% 95.89%
CHEMBL5103 Q969S8 Histone deacetylase 10 85.24% 90.08%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 83.98% 91.11%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.64% 93.03%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 82.46% 100.00%
CHEMBL226 P30542 Adenosine A1 receptor 81.38% 95.93%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.02% 100.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.73% 97.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.51% 89.00%
CHEMBL2535 P11166 Glucose transporter 80.48% 98.75%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11758398
LOTUS LTS0135000
wikiData Q77509481