MC-HilAba

Details

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Internal ID 05de2aba-1313-4b92-9b29-b8791817402f
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (5R,8S,11R,12S,15S,18S,19S,22R)-15-ethyl-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,5,12,19-tetramethyl-8-[(2S)-2-methylbutyl]-2-methylidene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclopentacosane-11,22-dicarboxylic acid
SMILES (Canonical) CCC1C(=O)NC(C(C(=O)NC(CCC(=O)N(C(=C)C(=O)NC(C(=O)NC(C(=O)NC(C(C(=O)N1)C)C(=O)O)CC(C)CC)C)C)C(=O)O)C)C=CC(=CC(C)C(CC2=CC=CC=C2)OC)C
SMILES (Isomeric) CC[C@H]1C(=O)N[C@H]([C@@H](C(=O)N[C@H](CCC(=O)N(C(=C)C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H]([C@@H](C(=O)N1)C)C(=O)O)C[C@@H](C)CC)C)C)C(=O)O)C)/C=C/C(=C/[C@H](C)[C@H](CC2=CC=CC=C2)OC)/C
InChI InChI=1S/C48H71N7O12/c1-12-26(3)24-37-46(62)54-40(48(65)66)30(7)42(58)50-34(13-2)45(61)51-35(20-19-27(4)23-28(5)38(67-11)25-33-17-15-14-16-18-33)29(6)41(57)52-36(47(63)64)21-22-39(56)55(10)32(9)44(60)49-31(8)43(59)53-37/h14-20,23,26,28-31,34-38,40H,9,12-13,21-22,24-25H2,1-8,10-11H3,(H,49,60)(H,50,58)(H,51,61)(H,52,57)(H,53,59)(H,54,62)(H,63,64)(H,65,66)/b20-19+,27-23+/t26-,28-,29-,30-,31+,34-,35-,36+,37-,38-,40+/m0/s1
InChI Key RHSLRMNOYRZULY-LKKIUZQFSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C48H71N7O12
Molecular Weight 938.10 g/mol
Exact Mass 937.51607073 g/mol
Topological Polar Surface Area (TPSA) 279.00 Ų
XlogP 4.60

Synonyms

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DTXSID801333793

2D Structure

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2D Structure of MC-HilAba

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.72% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.72% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 98.35% 83.82%
CHEMBL4072 P07858 Cathepsin B 97.73% 93.67%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.15% 95.56%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 95.04% 91.71%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.23% 86.33%
CHEMBL253 P34972 Cannabinoid CB2 receptor 90.20% 97.25%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 89.93% 97.64%
CHEMBL3060 Q9Y345 Glycine transporter 2 88.81% 99.17%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 87.49% 94.45%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.18% 95.89%
CHEMBL5103 Q969S8 Histone deacetylase 10 85.07% 90.08%
CHEMBL221 P23219 Cyclooxygenase-1 85.03% 90.17%
CHEMBL3837 P07711 Cathepsin L 83.23% 96.61%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.15% 97.14%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 82.75% 85.14%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 82.32% 95.89%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.12% 90.71%
CHEMBL1937 Q92769 Histone deacetylase 2 80.96% 94.75%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.41% 95.50%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.07% 99.23%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146684966
LOTUS LTS0082276
wikiData Q104246748