Manzamine C
| Internal ID | e7f05f7d-a70e-476b-8bf9-a27f2e0e8f0d |
| Taxonomy | Alkaloids and derivatives > Harmala alkaloids |
| IUPAC Name | 1-[2-[(6Z)-1-azacycloundec-6-en-1-yl]ethyl]-9H-pyrido[3,4-b]indole |
| SMILES (Canonical) | |
| SMILES (Isomeric) | |
| InChI | InChI=1S/C23H29N3/c1-2-4-6-10-17-26(16-9-5-3-1)18-14-22-23-20(13-15-24-22)19-11-7-8-12-21(19)25-23/h1-2,7-8,11-13,15,25H,3-6,9-10,14,16-18H2/b2-1- |
| InChI Key | LUYZVPNPJGYOIP-UPHRSURJSA-N |
| Popularity | 14 references in papers |
| Molecular Formula | C23H29N3 |
| Molecular Weight | 347.50 g/mol |
| Exact Mass | 347.236147938 g/mol |
| Topological Polar Surface Area (TPSA) | 31.90 Ų |
| XlogP | 5.20 |
| CHEMBL485902 |
| SCHEMBL11915471 |
| Target | Value | Probability (raw) | Probability (%) |
|---|---|---|---|
| No predicted properties yet! | |||
Proven Targets:
| CHEMBL ID | UniProt ID | Name | Min activity | Assay type | Source |
|---|---|---|---|---|---|
| No proven targets yet! | |||||
Predicted Targets (via Super-PRED):
| CHEMBL ID | UniProt ID | Name | Probability | Model accuracy |
|---|---|---|---|---|
| CHEMBL240 | Q12809 | HERG | 98.46% | 89.76% |
| CHEMBL255 | P29275 | Adenosine A2b receptor | 96.36% | 98.59% |
| CHEMBL3251 | P19838 | Nuclear factor NF-kappa-B p105 subunit | 96.03% | 96.09% |
| CHEMBL4261 | Q16665 | Hypoxia-inducible factor 1 alpha | 95.04% | 85.14% |
| CHEMBL3192 | Q9BY41 | Histone deacetylase 8 | 93.33% | 93.99% |
| CHEMBL3155 | P34969 | Serotonin 7 (5-HT7) receptor | 93.10% | 90.71% |
| CHEMBL3310 | Q96DB2 | Histone deacetylase 11 | 92.65% | 88.56% |
| CHEMBL2107 | P61073 | C-X-C chemokine receptor type 4 | 92.61% | 93.10% |
| CHEMBL2581 | P07339 | Cathepsin D | 92.08% | 98.95% |
| CHEMBL2095226 | P05556 | Integrin alpha-5/beta-1 | 91.82% | 96.39% |
| CHEMBL4208 | P20618 | Proteasome component C5 | 91.42% | 90.00% |
| CHEMBL253 | P34972 | Cannabinoid CB2 receptor | 90.33% | 97.25% |
| CHEMBL5103 | Q969S8 | Histone deacetylase 10 | 88.06% | 90.08% |
| CHEMBL1781 | P11387 | DNA topoisomerase I | 88.04% | 97.00% |
| CHEMBL1806 | P11388 | DNA topoisomerase II alpha | 87.56% | 89.00% |
| CHEMBL228 | P31645 | Serotonin transporter | 85.78% | 95.51% |
| CHEMBL335 | P18031 | Protein-tyrosine phosphatase 1B | 85.73% | 95.17% |
| CHEMBL2885 | P07451 | Carbonic anhydrase III | 85.35% | 87.45% |
| CHEMBL5747 | Q92793 | CREB-binding protein | 84.86% | 95.12% |
| CHEMBL3108638 | O15164 | Transcription intermediary factor 1-alpha | 84.86% | 95.56% |
| CHEMBL3902 | P09211 | Glutathione S-transferase Pi | 84.43% | 93.81% |
| CHEMBL2094121 | P14867 | GABA-A receptor; alpha-1/beta-3/gamma-2 | 84.23% | 95.50% |
| CHEMBL3476 | O15111 | Inhibitor of nuclear factor kappa B kinase alpha subunit | 84.06% | 95.83% |
| CHEMBL202 | P00374 | Dihydrofolate reductase | 84.00% | 89.92% |
| CHEMBL4803 | P29474 | Nitric-oxide synthase, endothelial | 83.99% | 86.00% |
| CHEMBL3492 | P49721 | Proteasome Macropain subunit | 83.13% | 90.24% |
| CHEMBL2095172 | P14867 | GABA-A receptor; alpha-1/beta-2/gamma-2 | 83.11% | 92.67% |
| CHEMBL5805 | Q9NR97 | Toll-like receptor 8 | 82.65% | 96.25% |
| CHEMBL2288 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 82.36% | 91.71% |
| CHEMBL1293249 | Q13887 | Kruppel-like factor 5 | 82.24% | 86.33% |
| CHEMBL2693 | Q9UIQ6 | Cystinyl aminopeptidase | 81.80% | 97.64% |
| CHEMBL2094127 | P06493 | Cyclin-dependent kinase 1/cyclin B | 81.67% | 96.00% |
| CHEMBL5619 | P27695 | DNA-(apurinic or apyrimidinic site) lyase | 81.36% | 91.11% |
| CHEMBL2378 | P30307 | Dual specificity phosphatase Cdc25C | 80.77% | 96.67% |
| CHEMBL1937 | Q92769 | Histone deacetylase 2 | 80.49% | 94.75% |
| CHEMBL2635 | P51452 | Dual specificity protein phosphatase 3 | 80.04% | 94.00% |
Below are displayed all the plants proven (via scientific papers) to contain this
compound!
To see more specific details click the taxa you are interested in.
To see more specific details click the taxa you are interested in.
| There are no matching plants. |
| PubChem | 9928254 |
| LOTUS | LTS0207630 |
| wikiData | Q104402998 |