Malyngamide R

Details

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Internal ID 83e396fd-3910-4098-8947-edf4a830b075
Taxonomy Lipids and lipid-like molecules > Fatty Acyls > Fatty amides > N-acyl amines
IUPAC Name (E,7S)-N-[(E,2Z)-2-(chloromethylidene)-6-[(2R)-2-(hydroxymethyl)-3-methoxy-5-oxo-2H-pyrrol-1-yl]-4-methoxy-6-oxohex-4-enyl]-7-methoxy-N-methyltetradec-4-enamide
SMILES (Canonical) CCCCCCCC(CC=CCCC(=O)N(C)CC(=CCl)CC(=CC(=O)N1C(C(=CC1=O)OC)CO)OC)OC
SMILES (Isomeric) CCCCCCC[C@@H](C/C=C/CCC(=O)N(C)C/C(=C\Cl)/C/C(=C\C(=O)N1[C@@H](C(=CC1=O)OC)CO)/OC)OC
InChI InChI=1S/C30H47ClN2O7/c1-6-7-8-9-11-14-24(38-3)15-12-10-13-16-28(35)32(2)21-23(20-31)17-25(39-4)18-29(36)33-26(22-34)27(40-5)19-30(33)37/h10,12,18-20,24,26,34H,6-9,11,13-17,21-22H2,1-5H3/b12-10+,23-20-,25-18+/t24-,26+/m0/s1
InChI Key NMCDAOMWRMOQIT-NFXWNFFPSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C30H47ClN2O7
Molecular Weight 583.20 g/mol
Exact Mass 582.3071795 g/mol
Topological Polar Surface Area (TPSA) 106.00 Ų
XlogP 4.30

Synonyms

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DTXSID501046911
(E,7S)-N-[(E,2Z)-2-(chloromethylidene)-6-[(2R)-2-(hydroxymethyl)-3-methoxy-5-oxo-2H-pyrrol-1-yl]-4-methoxy-6-oxohex-4-enyl]-7-methoxy-N-methyltetradec-4-enamide

2D Structure

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2D Structure of Malyngamide R

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.69% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.48% 96.09%
CHEMBL3060 Q9Y345 Glycine transporter 2 98.12% 99.17%
CHEMBL2581 P07339 Cathepsin D 97.39% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.04% 91.11%
CHEMBL1937 Q92769 Histone deacetylase 2 90.84% 94.75%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 89.80% 97.29%
CHEMBL5103 Q969S8 Histone deacetylase 10 89.36% 90.08%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 88.60% 92.86%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.01% 97.09%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 87.42% 94.33%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 86.77% 100.00%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 86.75% 92.88%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 86.07% 96.25%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.82% 95.56%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 84.70% 96.00%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 83.75% 91.81%
CHEMBL5255 O00206 Toll-like receptor 4 82.88% 92.50%
CHEMBL2996 Q05655 Protein kinase C delta 82.38% 97.79%
CHEMBL299 P17252 Protein kinase C alpha 82.23% 98.03%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.20% 100.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 81.88% 93.56%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 81.46% 97.50%
CHEMBL340 P08684 Cytochrome P450 3A4 81.44% 91.19%
CHEMBL3401 O75469 Pregnane X receptor 80.85% 94.73%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 21606577
LOTUS LTS0232773
wikiData Q77422651