Malevamide D

Details

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Internal ID 62a1fd94-794a-4a4f-aba4-d1a7481a2c23
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name [(2S)-1-hydroxy-3-phenylpropan-2-yl] (2R,3R)-3-[(2S)-1-[(3R,4S)-4-[[(2S)-2-[[(2S,3S)-2-(dimethylamino)-3-methylpentanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methoxy-5-methylhexanoyl]pyrrolidin-2-yl]-3-methoxy-2-methylpropanoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C40H68N4O8/c1-13-27(6)36(42(8)9)38(47)41-34(25(2)3)39(48)43(10)35(26(4)5)32(50-11)23-33(46)44-21-17-20-31(44)37(51-12)28(7)40(49)52-30(24-45)22-29-18-15-14-16-19-29/h14-16,18-19,25-28,30-32,34-37,45H,13,17,20-24H2,1-12H3,(H,41,47)/t27-,28+,30-,31-,32+,34-,35-,36-,37+/m0/s1
InChI Key LERBYHJLOKXDNI-UUFHNPECSA-N
Popularity 6 references in papers

Physical and Chemical Properties

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Molecular Formula C40H68N4O8
Molecular Weight 733.00 g/mol
Exact Mass 732.50371514 g/mol
Topological Polar Surface Area (TPSA) 138.00 Ų
XlogP 5.20

Synonyms

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CHEMBL453182
SCHEMBL17866994
DTXSID501046442

2D Structure

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2D Structure of Malevamide D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.88% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.23% 96.09%
CHEMBL3837 P07711 Cathepsin L 94.38% 96.61%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 93.37% 98.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.96% 95.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 92.93% 99.17%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.75% 95.89%
CHEMBL221 P23219 Cyclooxygenase-1 90.75% 90.17%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 88.87% 93.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.17% 95.89%
CHEMBL340 P08684 Cytochrome P450 3A4 87.04% 91.19%
CHEMBL4072 P07858 Cathepsin B 87.03% 93.67%
CHEMBL3359 P21462 Formyl peptide receptor 1 86.71% 93.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.64% 86.33%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.44% 96.47%
CHEMBL4208 P20618 Proteasome component C5 86.07% 90.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.87% 97.09%
CHEMBL5203 P33316 dUTP pyrophosphatase 85.61% 99.18%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.17% 97.14%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 84.05% 100.00%
CHEMBL1873 P00750 Tissue-type plasminogen activator 83.18% 93.33%
CHEMBL5028 O14672 ADAM10 81.32% 97.50%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.24% 90.71%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 81.14% 91.11%
CHEMBL237 P41145 Kappa opioid receptor 81.06% 98.10%
CHEMBL2514 O95665 Neurotensin receptor 2 80.11% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 636710
LOTUS LTS0111881
wikiData Q77565776