Macyranone B

Details

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Internal ID 0b8a31a3-f07e-48e5-bd19-41fb884a1ab6
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides
IUPAC Name (2S)-2-[[3-[[(2S,3R)-3-hydroxy-1-[[(2S,3S)-3-hydroxy-1-[[(2S)-4-methyl-1-[[2-(2-methylpropyl)-3-oxooxolan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]amino]-2-methyl-3-oxopropanoyl]amino]-3-phenylpropanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C35H53N5O11/c1-18(2)15-24(31(46)40-35(17-19(3)4)26(43)13-14-51-35)36-32(47)27(21(6)41)39-33(48)28(22(7)42)38-30(45)20(5)29(44)37-25(34(49)50)16-23-11-9-8-10-12-23/h8-12,18-22,24-25,27-28,41-42H,13-17H2,1-7H3,(H,36,47)(H,37,44)(H,38,45)(H,39,48)(H,40,46)(H,49,50)/t20?,21-,22+,24-,25-,27-,28-,35?/m0/s1
InChI Key MSPVQUNLNAOKSA-UGPVNDJUSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C35H53N5O11
Molecular Weight 719.80 g/mol
Exact Mass 719.37415752 g/mol
Topological Polar Surface Area (TPSA) 250.00 Ų
XlogP 1.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Macyranone B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.85% 98.95%
CHEMBL221 P23219 Cyclooxygenase-1 99.21% 90.17%
CHEMBL3837 P07711 Cathepsin L 98.43% 96.61%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.30% 91.11%
CHEMBL3359 P21462 Formyl peptide receptor 1 94.29% 93.56%
CHEMBL230 P35354 Cyclooxygenase-2 92.73% 89.63%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.67% 85.14%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 92.52% 98.33%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.49% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.45% 95.56%
CHEMBL268 P43235 Cathepsin K 90.43% 96.85%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 90.18% 85.11%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 89.61% 95.50%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 89.33% 97.14%
CHEMBL3060 Q9Y345 Glycine transporter 2 88.68% 99.17%
CHEMBL1255126 O15151 Protein Mdm4 87.46% 90.20%
CHEMBL4208 P20618 Proteasome component C5 86.62% 90.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 85.40% 86.33%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 85.01% 97.64%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.34% 94.45%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.26% 100.00%
CHEMBL5028 O14672 ADAM10 81.01% 97.50%
CHEMBL2514 O95665 Neurotensin receptor 2 80.70% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 122378444
LOTUS LTS0071164
wikiData Q105171341