Macrotermycin B

Details

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Internal ID 75e35ec4-c068-4ca0-a34e-ee92167fdd10
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbohydrates and carbohydrate conjugates > Glycosyl compounds > O-glycosyl compounds
IUPAC Name (1S,2R,5S,8S,9E,11Z,13S,18S,19R,20R)-2-[(2R,3S,4S,5S)-3-amino-4,5-dihydroxyoxan-2-yl]oxy-1,13-dimethyl-21-oxa-15-azatetracyclo[16.2.1.05,20.08,19]henicosa-3,6,9,11-tetraen-16-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C26H36N2O6/c1-14-5-3-4-6-15-7-8-16-9-10-19(33-25-23(27)24(31)17(29)13-32-25)26(2)22(16)21(15)18(34-26)11-20(30)28-12-14/h3-10,14-19,21-25,29,31H,11-13,27H2,1-2H3,(H,28,30)/b5-3-,6-4+/t14-,15-,16-,17-,18-,19+,21-,22+,23-,24+,25+,26+/m0/s1
InChI Key PMOMCJMPRBACKS-LBACZXMASA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C26H36N2O6
Molecular Weight 472.60 g/mol
Exact Mass 472.25733687 g/mol
Topological Polar Surface Area (TPSA) 123.00 Ų
XlogP 0.60

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Macrotermycin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.11% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.64% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.63% 94.45%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.45% 97.25%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 94.69% 92.88%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.06% 97.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.05% 85.14%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 90.29% 96.77%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.88% 95.56%
CHEMBL2581 P07339 Cathepsin D 89.68% 98.95%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 88.78% 94.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 88.77% 92.94%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.64% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.06% 95.89%
CHEMBL4208 P20618 Proteasome component C5 85.81% 90.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.67% 100.00%
CHEMBL218 P21554 Cannabinoid CB1 receptor 83.25% 96.61%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.24% 89.00%
CHEMBL4040 P28482 MAP kinase ERK2 83.14% 83.82%
CHEMBL3401 O75469 Pregnane X receptor 82.98% 94.73%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 82.68% 91.07%
CHEMBL226 P30542 Adenosine A1 receptor 81.95% 95.93%
CHEMBL255 P29275 Adenosine A2b receptor 81.31% 98.59%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.29% 99.23%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 81.20% 97.33%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 80.98% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 132821223
LOTUS LTS0135349
wikiData Q105211626