Leukotriene F4
Internal ID | 293ecb8a-edbf-427a-b790-151b083b1579 |
Taxonomy | Lipids and lipid-like molecules > Fatty Acyls > Eicosanoids > Leukotrienes |
IUPAC Name | (5S,6R,7E,9E,11Z,14Z)-6-[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-2-carboxyethyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid |
SMILES (Canonical) | CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)O)NC(=O)CCC(C(=O)O)N |
SMILES (Isomeric) | CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)O)NC(=O)CC[C@@H](C(=O)O)N |
InChI | InChI=1S/C28H44N2O8S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-24(23(31)15-14-17-26(33)34)39-20-22(28(37)38)30-25(32)19-18-21(29)27(35)36/h6-7,9-13,16,21-24,31H,2-5,8,14-15,17-20,29H2,1H3,(H,30,32)(H,33,34)(H,35,36)(H,37,38)/b7-6-,10-9-,12-11+,16-13+/t21-,22-,23-,24+/m0/s1 |
InChI Key | PYSODLWHFWCFLV-VJBFNVCUSA-N |
Popularity | 13 references in papers |
Molecular Formula | C28H44N2O8S |
Molecular Weight | 568.70 g/mol |
Exact Mass | 568.28183754 g/mol |
Topological Polar Surface Area (TPSA) | 213.00 Ų |
XlogP | 1.30 |
LTF4 |
83851-42-7 |
5S-hydroxy-6R-(S-glutamylcysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
Leukotriene F-4 |
LEUKOTRIENEF4 |
CHEBI:27491 |
5(S)-Hydroxy-6(R)-S-gamma-glutamylcysteine-7,9-trans-11,14-cis-eicosatetraenoic acid |
DTXSID901317172 |
LMFA03020009 |
AKOS040756243 |
There are more than 10 synonyms. If you wish to see them all click here. |
Target | Value | Probability (raw) | Probability (%) |
---|---|---|---|
No predicted properties yet! |
Proven Targets:
CHEMBL ID | UniProt ID | Name | Min activity | Assay type | Source |
---|---|---|---|---|---|
No proven targets yet! |
Predicted Targets (via Super-PRED):
CHEMBL ID | UniProt ID | Name | Probability | Model accuracy |
---|---|---|---|---|
CHEMBL2581 | P07339 | Cathepsin D | 99.55% | 98.95% |
CHEMBL3060 | Q9Y345 | Glycine transporter 2 | 99.45% | 99.17% |
CHEMBL230 | P35354 | Cyclooxygenase-2 | 97.33% | 89.63% |
CHEMBL221 | P23219 | Cyclooxygenase-1 | 97.23% | 90.17% |
CHEMBL2001 | Q9H244 | Purinergic receptor P2Y12 | 97.03% | 96.00% |
CHEMBL3251 | P19838 | Nuclear factor NF-kappa-B p105 subunit | 96.05% | 96.09% |
CHEMBL3976 | Q9UHL4 | Dipeptidyl peptidase II | 95.62% | 92.29% |
CHEMBL4769 | O95749 | Geranylgeranyl pyrophosphate synthetase | 93.31% | 92.08% |
CHEMBL5619 | P27695 | DNA-(apurinic or apyrimidinic site) lyase | 91.23% | 91.11% |
CHEMBL4040 | P28482 | MAP kinase ERK2 | 91.02% | 83.82% |
CHEMBL3359 | P21462 | Formyl peptide receptor 1 | 90.88% | 93.56% |
CHEMBL1255126 | O15151 | Protein Mdm4 | 89.63% | 90.20% |
CHEMBL5845 | P23415 | Glycine receptor subunit alpha-1 | 88.60% | 90.71% |
CHEMBL236 | P41143 | Delta opioid receptor | 88.35% | 99.35% |
CHEMBL1293267 | Q9HC97 | G-protein coupled receptor 35 | 88.08% | 89.34% |
CHEMBL4227 | P25090 | Lipoxin A4 receptor | 88.03% | 100.00% |
CHEMBL4657 | Q6V1X1 | Dipeptidyl peptidase VIII | 87.96% | 97.21% |
CHEMBL2413 | P32246 | C-C chemokine receptor type 1 | 87.91% | 89.50% |
CHEMBL4793 | Q86TI2 | Dipeptidyl peptidase IX | 87.50% | 96.95% |
CHEMBL1907591 | P30926 | Neuronal acetylcholine receptor; alpha4/beta4 | 86.76% | 100.00% |
CHEMBL1075094 | Q16236 | Nuclear factor erythroid 2-related factor 2 | 85.92% | 96.00% |
CHEMBL3130 | O00329 | PI3-kinase p110-delta subunit | 84.81% | 96.47% |
CHEMBL340 | P08684 | Cytochrome P450 3A4 | 83.59% | 91.19% |
CHEMBL4203 | Q9HAZ1 | Dual specificity protein kinase CLK4 | 83.55% | 94.45% |
CHEMBL5163 | Q9NY46 | Sodium channel protein type III alpha subunit | 83.30% | 96.90% |
CHEMBL3892 | Q99500 | Sphingosine 1-phosphate receptor Edg-3 | 82.94% | 97.29% |
CHEMBL2111367 | P27986 | PI3-kinase p110-alpha/p85-alpha | 82.38% | 94.33% |
CHEMBL2514 | O95665 | Neurotensin receptor 2 | 82.35% | 100.00% |
CHEMBL1781 | P11387 | DNA topoisomerase I | 81.95% | 97.00% |
CHEMBL3108638 | O15164 | Transcription intermediary factor 1-alpha | 81.07% | 95.56% |
CHEMBL3807 | P17706 | T-cell protein-tyrosine phosphatase | 80.13% | 93.00% |
Below are displayed all the plants proven (via scientific papers) to contain this
compound!
To see more specific details click the taxa you are interested in.
To see more specific details click the taxa you are interested in.
Arabidopsis thaliana |
PubChem | 5280938 |
LOTUS | LTS0005336 |
wikiData | Q27103162 |