Leucyl-3-epi-deoxynegamycin

Details

Top
Internal ID 4a160750-22ae-45f4-a6d5-53bcbae42e14
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives
IUPAC Name 2-[[[(3S)-6-amino-3-[[(2S)-2-amino-4-methylpentanoyl]amino]hexanoyl]amino]-methylamino]acetic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C15H31N5O4/c1-10(2)7-12(17)15(24)18-11(5-4-6-16)8-13(21)19-20(3)9-14(22)23/h10-12H,4-9,16-17H2,1-3H3,(H,18,24)(H,19,21)(H,22,23)/t11-,12-/m0/s1
InChI Key DOTQAYWMWCUEBC-RYUDHWBXSA-N
Popularity 4 references in papers

Physical and Chemical Properties

Top
Molecular Formula C15H31N5O4
Molecular Weight 345.44 g/mol
Exact Mass 345.23760449 g/mol
Topological Polar Surface Area (TPSA) 151.00 Ų
XlogP -3.00

Synonyms

Top
CHEMBL4159899
SCHEMBL16280592

2D Structure

Top
2D Structure of Leucyl-3-epi-deoxynegamycin

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.20% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.59% 96.09%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 96.04% 96.95%
CHEMBL1255126 O15151 Protein Mdm4 95.40% 90.20%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 94.68% 96.47%
CHEMBL221 P23219 Cyclooxygenase-1 93.97% 90.17%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 93.34% 97.21%
CHEMBL3060 Q9Y345 Glycine transporter 2 93.27% 99.17%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 93.11% 92.29%
CHEMBL3359 P21462 Formyl peptide receptor 1 92.02% 93.56%
CHEMBL4040 P28482 MAP kinase ERK2 90.75% 83.82%
CHEMBL2514 O95665 Neurotensin receptor 2 90.21% 100.00%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 89.34% 100.00%
CHEMBL340 P08684 Cytochrome P450 3A4 89.28% 91.19%
CHEMBL2094135 Q96BI3 Gamma-secretase 88.70% 98.05%
CHEMBL237 P41145 Kappa opioid receptor 88.30% 98.10%
CHEMBL4618 P09960 Leukotriene A4 hydrolase 87.24% 97.86%
CHEMBL230 P35354 Cyclooxygenase-2 86.64% 89.63%
CHEMBL3492 P49721 Proteasome Macropain subunit 86.28% 90.24%
CHEMBL3776 Q14790 Caspase-8 86.12% 97.06%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 85.94% 97.29%
CHEMBL236 P41143 Delta opioid receptor 85.38% 99.35%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.69% 90.71%
CHEMBL3837 P07711 Cathepsin L 84.08% 96.61%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 83.93% 94.33%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 82.63% 96.90%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 82.59% 98.75%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 82.48% 98.33%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.21% 93.00%
CHEMBL3308 P55212 Caspase-6 82.09% 97.56%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.80% 96.00%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 81.28% 93.10%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 80.11% 95.71%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 102439777
LOTUS LTS0093421
wikiData Q104986192