Leopolic acid A

Details

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Internal ID 691c2943-6562-4720-849c-ea01d801741c
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives > Phenylalanine and derivatives
IUPAC Name (2S)-2-[[(2S)-1-(3-decyl-4-hydroxy-5-oxo-2H-pyrrol-1-yl)-3-methyl-1-oxobutan-2-yl]carbamoylamino]-3-phenylpropanoic acid
SMILES (Canonical) CCCCCCCCCCC1=C(C(=O)N(C1)C(=O)C(C(C)C)NC(=O)NC(CC2=CC=CC=C2)C(=O)O)O
SMILES (Isomeric) CCCCCCCCCCC1=C(C(=O)N(C1)C(=O)[C@H](C(C)C)NC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)O
InChI InChI=1S/C29H43N3O6/c1-4-5-6-7-8-9-10-14-17-22-19-32(27(35)25(22)33)26(34)24(20(2)3)31-29(38)30-23(28(36)37)18-21-15-12-11-13-16-21/h11-13,15-16,20,23-24,33H,4-10,14,17-19H2,1-3H3,(H,36,37)(H2,30,31,38)/t23-,24-/m0/s1
InChI Key BSVQYPWIIRMJLD-ZEQRLZLVSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C29H43N3O6
Molecular Weight 529.70 g/mol
Exact Mass 529.31518610 g/mol
Topological Polar Surface Area (TPSA) 136.00 Ų
XlogP 6.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Leopolic acid A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.86% 98.95%
CHEMBL4072 P07858 Cathepsin B 99.26% 93.67%
CHEMBL221 P23219 Cyclooxygenase-1 98.74% 90.17%
CHEMBL4040 P28482 MAP kinase ERK2 98.34% 83.82%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 94.65% 91.81%
CHEMBL230 P35354 Cyclooxygenase-2 93.30% 89.63%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.79% 94.45%
CHEMBL3359 P21462 Formyl peptide receptor 1 92.64% 93.56%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 92.36% 92.08%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.34% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.91% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.04% 95.56%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 90.07% 98.33%
CHEMBL3060 Q9Y345 Glycine transporter 2 89.69% 99.17%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.00% 86.33%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.92% 90.71%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 87.24% 100.00%
CHEMBL268 P43235 Cathepsin K 86.36% 96.85%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 84.56% 100.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 83.15% 97.64%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.29% 93.00%
CHEMBL1255126 O15151 Protein Mdm4 82.18% 90.20%
CHEMBL3004 P33527 Multidrug resistance-associated protein 1 81.18% 96.37%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.19% 96.47%
CHEMBL1781 P11387 DNA topoisomerase I 80.05% 97.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 71482889
LOTUS LTS0201664
wikiData Q77484763