Latifoline N-oxide

Details

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Internal ID 72d34b81-9a45-4ed6-b04c-cec36d4f0f90
Taxonomy Alkaloids and derivatives
IUPAC Name [7-[(3,5-dimethyl-2-oxo-3H-furan-4-carbonyl)peroxymethyl]-4-oxido-2,3,5,8-tetrahydro-1H-pyrrolizin-4-ium-1-yl] 2-methylbutanoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H27NO8/c1-5-11(2)18(22)28-15-7-9-21(25)8-6-14(17(15)21)10-26-29-20(24)16-12(3)19(23)27-13(16)4/h6,11-12,15,17H,5,7-10H2,1-4H3
InChI Key JFRJYXOOUABEPQ-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C20H27NO8
Molecular Weight 409.40 g/mol
Exact Mass 409.17366682 g/mol
Topological Polar Surface Area (TPSA) 106.00 Ų
XlogP 1.40

Synonyms

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98752-06-8
[7-[(3,5-dimethyl-2-oxo-3H-furan-4-carbonyl)peroxymethyl]-4-oxido-2,3,5,8-tetrahydro-1H-pyrrolizin-4-ium-1-yl] 2-methylbutanoate
Latifoline-N-oxide
DTXSID60913102
AKOS040733995
7-{[(2,4-Dimethyl-5-oxo-4,5-dihydrofuran-3-carbonyl)peroxy]methyl}-4-oxo-1,2,3,4,5,7a-hexahydro-4lambda~5~-pyrrolizin-1-yl 2-methylbutanoate

2D Structure

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2D Structure of Latifoline N-oxide

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.11% 98.95%
CHEMBL4072 P07858 Cathepsin B 95.36% 93.67%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.37% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.83% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.15% 99.23%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 85.55% 96.47%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.19% 99.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.06% 97.09%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.46% 93.56%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.43% 94.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 82.41% 97.25%
CHEMBL5255 O00206 Toll-like receptor 4 82.14% 92.50%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.05% 86.33%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 80.99% 93.65%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.92% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Hackelia floribunda

Cross-Links

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PubChem 179107
LOTUS LTS0132982
wikiData Q82883630