2-Isobutyl-5-(3-indolyl)oxazole

Details

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Internal ID ced8bd05-cb88-4085-96b1-66fbdb858895
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Indoles
IUPAC Name 5-(1H-indol-3-yl)-2-(2-methylpropyl)-1,3-oxazole
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C15H16N2O/c1-10(2)7-15-17-9-14(18-15)12-8-16-13-6-4-3-5-11(12)13/h3-6,8-10,16H,7H2,1-2H3
InChI Key DJGNEEKCRPWTKI-UHFFFAOYSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C15H16N2O
Molecular Weight 240.30 g/mol
Exact Mass 240.126263138 g/mol
Topological Polar Surface Area (TPSA) 41.80 Ų
XlogP 3.80

Synonyms

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5-(1H-Indol-3-yl)-2-isobutyloxazole
477951-20-5
5-(1H-indol-3-yl)-2-(2-methylpropyl)-1,3-oxazole
CHEMBL464484
SCHEMBL12318442
2-isobutyl-5-(3-indolyl)oxazole
3-(2-Isobutyl-oxazol-5-yl)-1H-indole
3-(2-isobutyl-1,3-oxazol-5-yl)-1H-indole
1H-indole, 3-[2-(2-methylpropyl)-5-oxazolyl]-
InChI=1/C15H16N2O/c1-10(2)7-15-17-9-14(18-15)12-8-16-13-6-4-3-5-11(12)13/h3-6,8-10,16H,7H2,1-2H

2D Structure

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2D Structure of 2-Isobutyl-5-(3-indolyl)oxazole

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 93.52% 98.95%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 91.82% 94.62%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.44% 94.00%
CHEMBL1907 P15144 Aminopeptidase N 91.18% 93.31%
CHEMBL3310 Q96DB2 Histone deacetylase 11 90.50% 88.56%
CHEMBL1951 P21397 Monoamine oxidase A 90.01% 91.49%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.77% 91.11%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 89.33% 85.30%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.48% 95.56%
CHEMBL3401 O75469 Pregnane X receptor 87.23% 94.73%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.20% 96.09%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 86.10% 95.71%
CHEMBL2535 P11166 Glucose transporter 85.93% 98.75%
CHEMBL3492 P49721 Proteasome Macropain subunit 84.76% 90.24%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.42% 89.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 84.23% 93.99%
CHEMBL3902 P09211 Glutathione S-transferase Pi 83.57% 93.81%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 83.18% 96.67%
CHEMBL2996 Q05655 Protein kinase C delta 83.14% 97.79%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 82.72% 92.67%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 82.46% 93.65%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.92% 86.33%
CHEMBL221 P23219 Cyclooxygenase-1 81.65% 90.17%
CHEMBL2716 Q8WUI4 Histone deacetylase 7 81.21% 89.44%
CHEMBL2850 P49840 Glycogen synthase kinase-3 alpha 80.24% 88.84%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 637460
LOTUS LTS0047253
wikiData Q77281482