Klymollin F

Details

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Internal ID 4c1cdd28-1faf-42d5-bd48-c9afdf9f23bc
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Cladiellane diterpenoids
IUPAC Name [(1R,2R,3R,4S,5S,6S,7S,8R,10S,11S,14R)-4,5,14-triacetyloxy-10-hydroxy-10,14-dimethyl-3-propan-2-ylspiro[15-oxatricyclo[6.6.1.02,7]pentadecane-6,2'-oxirane]-11-yl] tetradecanoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C40H66O11/c1-9-10-11-12-13-14-15-16-17-18-19-20-31(44)50-30-21-22-39(8,51-28(6)43)36-33-32(25(2)3)35(47-26(4)41)37(48-27(5)42)40(24-46-40)34(33)29(49-36)23-38(30,7)45/h25,29-30,32-37,45H,9-24H2,1-8H3/t29-,30+,32-,33-,34-,35+,36-,37+,38+,39-,40-/m1/s1
InChI Key QFRHIDBSBWFQMK-LGGODAECSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C40H66O11
Molecular Weight 722.90 g/mol
Exact Mass 722.46051292 g/mol
Topological Polar Surface Area (TPSA) 147.00 Ų
XlogP 8.00

Synonyms

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CHEBI:68956
Rel-Klymollin F
CHEMBL1923040
Q27137306
rel-(1S,2S,3S,4R,4aR,5R,6R,9S,10S,12R,12aS)-2,3,6-tris(acetyloxy)-10-hydroxy-6,10-dimethyl-4-(propan-2-yl)dodecahydro-2H-spiro[5,12-epoxybenzo[10]annulene-1,2'-oxiran]-9-yl tetradecanoate

2D Structure

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2D Structure of Klymollin F

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.02% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.76% 97.25%
CHEMBL2996 Q05655 Protein kinase C delta 97.63% 97.79%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.10% 94.45%
CHEMBL299 P17252 Protein kinase C alpha 96.90% 98.03%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 96.17% 97.29%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 95.87% 92.86%
CHEMBL1293316 Q9HBX9 Relaxin receptor 1 95.45% 82.50%
CHEMBL5255 O00206 Toll-like receptor 4 95.45% 92.50%
CHEMBL2581 P07339 Cathepsin D 95.37% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.00% 91.11%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 92.49% 100.00%
CHEMBL340 P08684 Cytochrome P450 3A4 91.39% 91.19%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 90.78% 92.62%
CHEMBL3060 Q9Y345 Glycine transporter 2 90.60% 99.17%
CHEMBL230 P35354 Cyclooxygenase-2 90.17% 89.63%
CHEMBL4227 P25090 Lipoxin A4 receptor 90.08% 100.00%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 89.80% 89.05%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 89.50% 96.47%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 89.24% 91.24%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 88.99% 85.94%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 88.59% 95.50%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 87.77% 82.69%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 87.66% 94.33%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.35% 85.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.24% 97.09%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 85.20% 97.47%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 85.18% 96.77%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 85.16% 97.50%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.09% 97.14%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.46% 99.23%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 84.08% 96.38%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.02% 100.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.35% 93.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.71% 95.89%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 80.86% 95.17%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 80.61% 95.71%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.22% 93.56%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 56655568
LOTUS LTS0125932
wikiData Q27137306