Kitacinnamycin G

Details

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Internal ID 267ef30a-cce9-4753-9785-e97c0c489593
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (E)-N-[(3S,6S,15R,18S,21S,24R,27R,28R)-24-(2-amino-2-oxoethyl)-18-benzyl-19,28-dimethyl-3-(2-methylpropyl)-2,5,8,11,14,17,20,23,26-nonaoxo-6,15,21-tri(propan-2-yl)-1-oxa-4,7,10,13,16,19,22,25-octazacyclooctacos-27-yl]-3-[2-[(E)-prop-1-enyl]phenyl]prop-2-enamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C55H78N10O12/c1-12-18-36-21-16-17-22-37(36)23-24-42(67)61-48-34(10)77-55(76)39(25-30(2)3)60-52(73)46(32(6)7)62-44(69)29-57-43(68)28-58-51(72)45(31(4)5)63-50(71)40(26-35-19-14-13-15-20-35)65(11)54(75)47(33(8)9)64-49(70)38(27-41(56)66)59-53(48)74/h12-24,30-34,38-40,45-48H,25-29H2,1-11H3,(H2,56,66)(H,57,68)(H,58,72)(H,59,74)(H,60,73)(H,61,67)(H,62,69)(H,63,71)(H,64,70)/b18-12+,24-23+/t34-,38-,39+,40+,45-,46+,47+,48-/m1/s1
InChI Key WZVJFWXQTVKYAX-AFPCMDACSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C55H78N10O12
Molecular Weight 1071.30 g/mol
Exact Mass 1070.58006796 g/mol
Topological Polar Surface Area (TPSA) 323.00 Ų
XlogP 4.40

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Kitacinnamycin G

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.59% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.91% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.78% 95.56%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.52% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 95.06% 85.14%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 94.99% 97.64%
CHEMBL221 P23219 Cyclooxygenase-1 94.81% 90.17%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 94.43% 93.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.15% 86.33%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.08% 89.00%
CHEMBL3384 Q16512 Protein kinase N1 88.99% 80.71%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 88.39% 95.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 87.79% 94.45%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.19% 96.47%
CHEMBL1949 P62937 Cyclophilin A 84.95% 98.57%
CHEMBL5103 Q969S8 Histone deacetylase 10 83.69% 90.08%
CHEMBL3891 P07384 Calpain 1 82.97% 93.04%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 82.90% 96.00%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 81.98% 89.67%
CHEMBL255 P29275 Adenosine A2b receptor 81.69% 98.59%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.65% 97.14%
CHEMBL4071 P08311 Cathepsin G 81.09% 94.64%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.03% 99.17%
CHEMBL4208 P20618 Proteasome component C5 80.60% 90.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 80.44% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146682818
LOTUS LTS0164153
wikiData Q105323567