Istamycin C1

Details

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Internal ID 2f8717e6-539f-4ffb-ba0f-2dc0ba665fe3
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbohydrates and carbohydrate conjugates > Aminosaccharides > Aminoglycosides > Aminocyclitol glycosides
IUPAC Name N-[(1S,2R,3R,4S,6S)-4-amino-3-[(2R,3R,6S)-3-amino-6-(ethylaminomethyl)oxan-2-yl]oxy-2-hydroxy-6-methoxycyclohexyl]-2-formamido-N-methylacetamide
SMILES (Canonical) CCNCC1CCC(C(O1)OC2C(CC(C(C2O)N(C)C(=O)CNC=O)OC)N)N
SMILES (Isomeric) CCNC[C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@@H]([C@H]([C@H]2O)N(C)C(=O)CNC=O)OC)N)N
InChI InChI=1S/C19H37N5O6/c1-4-22-8-11-5-6-12(20)19(29-11)30-18-13(21)7-14(28-3)16(17(18)27)24(2)15(26)9-23-10-25/h10-14,16-19,22,27H,4-9,20-21H2,1-3H3,(H,23,25)/t11-,12+,13-,14-,16+,17+,18+,19+/m0/s1
InChI Key HEQBQGYOPQNTBN-XIDLQPTCSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C19H37N5O6
Molecular Weight 431.50 g/mol
Exact Mass 431.27438392 g/mol
Topological Polar Surface Area (TPSA) 161.00 Ų
XlogP -2.70

Synonyms

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CHEBI:81447
C17996
Q27155380

2D Structure

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2D Structure of Istamycin C1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4040 P28482 MAP kinase ERK2 99.35% 83.82%
CHEMBL3137262 O60341 LSD1/CoREST complex 96.17% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.85% 96.09%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 94.06% 96.95%
CHEMBL3060 Q9Y345 Glycine transporter 2 92.91% 99.17%
CHEMBL204 P00734 Thrombin 90.97% 96.01%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.51% 91.11%
CHEMBL2581 P07339 Cathepsin D 89.66% 98.95%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 89.38% 96.77%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 89.28% 94.33%
CHEMBL1974 P36888 Tyrosine-protein kinase receptor FLT3 88.95% 91.83%
CHEMBL6136 O60341 Lysine-specific histone demethylase 1 86.91% 95.58%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.50% 89.00%
CHEMBL226 P30542 Adenosine A1 receptor 83.80% 95.93%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 83.47% 95.50%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 83.13% 97.50%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.81% 95.56%
CHEMBL4015 P41597 C-C chemokine receptor type 2 82.70% 98.57%
CHEMBL340 P08684 Cytochrome P450 3A4 82.44% 91.19%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.00% 92.62%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 81.88% 95.89%
CHEMBL5255 O00206 Toll-like receptor 4 81.45% 92.50%
CHEMBL4072 P07858 Cathepsin B 81.29% 93.67%
CHEMBL3401 O75469 Pregnane X receptor 81.26% 94.73%
CHEMBL2664 P23526 Adenosylhomocysteinase 81.19% 86.67%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.14% 96.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.75% 97.14%
CHEMBL5028 O14672 ADAM10 80.49% 97.50%
CHEMBL3922 P50579 Methionine aminopeptidase 2 80.23% 97.28%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 46174030
LOTUS LTS0009793
wikiData Q27155380