YM-51084

Details

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Internal ID 4a933599-c2f8-4f66-8dfe-50182b91f65a
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides
IUPAC Name (2S)-2-[[(2R)-3-(4-hydroxyphenyl)-2-(3-methylbutanoylamino)propanoyl]amino]-3-methyl-N-[(2R)-1-oxo-3-phenylpropan-2-yl]butanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C28H37N3O5/c1-18(2)14-25(34)30-24(16-21-10-12-23(33)13-11-21)27(35)31-26(19(3)4)28(36)29-22(17-32)15-20-8-6-5-7-9-20/h5-13,17-19,22,24,26,33H,14-16H2,1-4H3,(H,29,36)(H,30,34)(H,31,35)/t22-,24-,26+/m1/s1
InChI Key MWFNFXJJXCNWSP-NOOIUNMQSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C28H37N3O5
Molecular Weight 495.60 g/mol
Exact Mass 495.27332129 g/mol
Topological Polar Surface Area (TPSA) 125.00 Ų
XlogP 2.40

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of YM-51084

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.82% 98.95%
CHEMBL4072 P07858 Cathepsin B 99.08% 93.67%
CHEMBL3837 P07711 Cathepsin L 97.75% 96.61%
CHEMBL1255126 O15151 Protein Mdm4 96.17% 90.20%
CHEMBL3060 Q9Y345 Glycine transporter 2 95.16% 99.17%
CHEMBL3492 P49721 Proteasome Macropain subunit 95.11% 90.24%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.70% 95.56%
CHEMBL3891 P07384 Calpain 1 93.61% 93.04%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 93.59% 97.23%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 93.27% 100.00%
CHEMBL4801 P29466 Caspase-1 93.10% 96.85%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 91.89% 95.50%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.89% 91.11%
CHEMBL2535 P11166 Glucose transporter 90.51% 98.75%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 88.68% 89.33%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 88.24% 94.45%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 84.43% 96.67%
CHEMBL4208 P20618 Proteasome component C5 84.41% 90.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 84.18% 96.09%
CHEMBL4973 P43004 Excitatory amino acid transporter 2 82.80% 98.75%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 82.23% 95.89%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 82.15% 91.71%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 81.95% 90.93%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 81.65% 93.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 81.37% 93.56%
CHEMBL2514 O95665 Neurotensin receptor 2 81.31% 100.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.80% 90.71%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 80.29% 99.15%
CHEMBL3401 O75469 Pregnane X receptor 80.15% 94.73%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 9827119
LOTUS LTS0194467
wikiData Q77512964