Isorobustin

Details

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Internal ID 1c5a96ae-a41b-4e7d-8fe7-a3beea6852fd
Taxonomy Phenylpropanoids and polyketides > Isoflavonoids > Pyranoisoflavonoids
IUPAC Name 3-(1,3-benzodioxol-5-yl)-4-hydroxy-5-methoxy-8,8-dimethylpyrano[2,3-h]chromen-2-one
SMILES (Canonical) CC1(C=CC2=C3C(=C(C=C2O1)OC)C(=C(C(=O)O3)C4=CC5=C(C=C4)OCO5)O)C
SMILES (Isomeric) CC1(C=CC2=C3C(=C(C=C2O1)OC)C(=C(C(=O)O3)C4=CC5=C(C=C4)OCO5)O)C
InChI InChI=1S/C22H18O7/c1-22(2)7-6-12-14(29-22)9-16(25-3)18-19(23)17(21(24)28-20(12)18)11-4-5-13-15(8-11)27-10-26-13/h4-9,23H,10H2,1-3H3
InChI Key IPSRAWJCFVMJBQ-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C22H18O7
Molecular Weight 394.40 g/mol
Exact Mass 394.10525291 g/mol
Topological Polar Surface Area (TPSA) 83.40 Ų
XlogP 3.60

Synonyms

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LMPK12160030

2D Structure

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2D Structure of Isorobustin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.70% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 99.24% 94.45%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 98.94% 96.77%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 96.61% 80.96%
CHEMBL2581 P07339 Cathepsin D 96.40% 98.95%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 95.85% 94.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 95.05% 86.33%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 94.36% 85.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 94.25% 89.00%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 93.66% 85.30%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 91.56% 92.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.08% 95.56%
CHEMBL2292 Q13627 Dual-specificity tyrosine-phosphorylation regulated kinase 1A 87.08% 93.24%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.95% 95.89%
CHEMBL2146302 O94925 Glutaminase kidney isoform, mitochondrial 86.53% 100.00%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 85.48% 94.80%
CHEMBL4208 P20618 Proteasome component C5 84.51% 90.00%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 83.64% 99.15%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.38% 99.23%
CHEMBL2535 P11166 Glucose transporter 82.03% 98.75%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 81.43% 96.09%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 80.65% 96.67%
CHEMBL1937 Q92769 Histone deacetylase 2 80.31% 94.75%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.23% 90.71%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Deguelia spruceana

Cross-Links

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PubChem 54739056
LOTUS LTS0094009
wikiData Q105117475