(11S)-10Alpha-Hydroxy-3-Oxoguaia-4-Eno-12,6Alpha-Lactone

Details

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Internal ID 6fe47acd-a9c0-48a1-a418-3a444071c31c
Taxonomy Organoheterocyclic compounds > Lactones > Gamma butyrolactones
IUPAC Name (3S,3aS,6R,6aR,9bS)-6-hydroxy-3,6,9-trimethyl-3a,4,5,6a,7,9b-hexahydro-3H-azuleno[4,5-b]furan-2,8-dione
SMILES (Canonical) CC1C2CCC(C3CC(=O)C(=C3C2OC1=O)C)(C)O
SMILES (Isomeric) C[C@H]1[C@@H]2CC[C@@]([C@@H]3CC(=O)C(=C3[C@H]2OC1=O)C)(C)O
InChI InChI=1S/C15H20O4/c1-7-9-4-5-15(3,18)10-6-11(16)8(2)12(10)13(9)19-14(7)17/h7,9-10,13,18H,4-6H2,1-3H3/t7-,9-,10+,13-,15+/m0/s1
InChI Key FUKGETHUQZLZRJ-YIUCUBBLSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C15H20O4
Molecular Weight 264.32 g/mol
Exact Mass 264.13615911 g/mol
Topological Polar Surface Area (TPSA) 63.60 Ų
XlogP 0.60

Synonyms

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(3S,3aS,6R,6aR,9bS)-6-hydroxy-3,6,9-trimethyl-3a,4,5,6a,7,9b-hexahydro-3H-azuleno[4,5-b]furan-2,8-dione
(3S,3aS,6R,6aR,9bS)-6-hydroxy-3,6,9-trimethyl-3a,4,5,6a,7,9b-hexahydro-3H-azuleno(4,5-b)furan-2,8-dione
RefChem:68184
(11S)-10alpha-hydroxy-3-oxoguaia-4-eno-12,6alpha-lactone
(3S)-3abeta,4,5,6,6abeta,9balpha-Hexahydro-3,6,9-trimethyl-6beta-hydroxyazuleno[4,5-b]furan-2,8(3H,7H)-dione
CHEMBL516875

2D Structure

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2D Structure of (11S)-10Alpha-Hydroxy-3-Oxoguaia-4-Eno-12,6Alpha-Lactone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.38% 95.56%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.07% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.72% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.66% 99.23%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.63% 85.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.48% 97.09%
CHEMBL325 Q13547 Histone deacetylase 1 84.35% 95.92%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 84.25% 96.09%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.48% 97.14%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 82.91% 94.80%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.52% 100.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 82.28% 93.03%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.16% 89.00%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 81.68% 93.04%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Ixeris chinensis

Cross-Links

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PubChem 14263690
NPASS NPC32922
ChEMBL CHEMBL516875
LOTUS LTS0258458
wikiData Q105001807