Isochromophilone A

Details

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Internal ID 372f4f80-e753-493b-9a99-a47b341c27d0
Taxonomy Organoheterocyclic compounds > Pyrans
IUPAC Name (6R,6aR,9S,9aS)-9-acetyl-5-chloro-3-[(1E,3E,5S)-3,5-dimethylhepta-1,3-dienyl]-6-hydroxy-6a-methyl-9,9a-dihydro-6H-furo[2,3-h]isochromen-8-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C23H27ClO5/c1-6-12(2)9-13(3)7-8-15-10-16-17(11-28-15)19-18(14(4)25)22(27)29-23(19,5)21(26)20(16)24/h7-12,18-19,21,26H,6H2,1-5H3/b8-7+,13-9+/t12-,18+,19+,21-,23+/m0/s1
InChI Key KLSDJLUKJAUCQO-RTGWHNKHSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C23H27ClO5
Molecular Weight 418.90 g/mol
Exact Mass 418.1547017 g/mol
Topological Polar Surface Area (TPSA) 72.80 Ų
XlogP 3.50

Synonyms

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CHEMBL4292076

2D Structure

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2D Structure of Isochromophilone A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.83% 94.45%
CHEMBL2581 P07339 Cathepsin D 97.09% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.58% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.24% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 92.29% 97.25%
CHEMBL3401 O75469 Pregnane X receptor 92.12% 94.73%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 90.41% 94.80%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.75% 86.33%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 89.54% 96.00%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 88.26% 89.34%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 88.21% 85.30%
CHEMBL3060 Q9Y345 Glycine transporter 2 87.96% 99.17%
CHEMBL1937 Q92769 Histone deacetylase 2 87.75% 94.75%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.70% 95.56%
CHEMBL226 P30542 Adenosine A1 receptor 86.45% 95.93%
CHEMBL221 P23219 Cyclooxygenase-1 86.34% 90.17%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.95% 89.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139589930
LOTUS LTS0078545
wikiData Q105142795