Isariotin B

Details

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Internal ID 9faa8631-beb4-4ab4-a868-695f8e38fa11
Taxonomy Lipids and lipid-like molecules > Fatty Acyls > Fatty acids and conjugates > Medium-chain fatty acids
IUPAC Name (E)-12-oxo-12-[[(1S,2S,4S,5S,6S,7R,8S)-1,5,7-trihydroxy-10-oxo-3-oxatricyclo[4.3.1.02,4]decan-8-yl]amino]dodec-10-enoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H31NO8/c23-13(9-7-5-3-1-2-4-6-8-10-14(24)25)22-12-11-21(29)19(28)15(16(12)26)17(27)18-20(21)30-18/h7,9,12,15-18,20,26-27,29H,1-6,8,10-11H2,(H,22,23)(H,24,25)/b9-7+/t12-,15-,16-,17-,18-,20-,21+/m0/s1
InChI Key GCOQLRRFBKJAPF-DBGSMAKUSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C21H31NO8
Molecular Weight 425.50 g/mol
Exact Mass 425.20496695 g/mol
Topological Polar Surface Area (TPSA) 157.00 Ų
XlogP 0.30

Synonyms

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(E)-12-oxo-12-[[(1S,2S,4S,5S,6S,7R,8S)-1,5,7-trihydroxy-10-oxo-3-oxatricyclo[4.3.1.02,4]decan-8-yl]amino]dodec-10-enoic acid
(E)-12-oxo-12-(((1S,2S,4S,5S,6S,7R,8S)-1,5,7-trihydroxy-10-oxo-3-oxatricyclo(4.3.1.02,4)decan-8-yl)amino)dodec-10-enoic acid
11-((1,5,7-trihydroxy-10-oxo-3-oxatricyclo(4.3.1.0,)decan-8-yl)-C-hydroxycarbonimidoyl)undec-10-enoate
11-({1,5,7-trihydroxy-10-oxo-3-oxatricyclo[4.3.1.0,]decan-8-yl}-C-hydroxycarbonimidoyl)undec-10-enoate
RefChem:148898
952703-97-8
CHEMBL253124
CHEBI:205760

2D Structure

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2D Structure of Isariotin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.30% 91.11%
CHEMBL221 P23219 Cyclooxygenase-1 96.60% 90.17%
CHEMBL3060 Q9Y345 Glycine transporter 2 94.85% 99.17%
CHEMBL4040 P28482 MAP kinase ERK2 94.37% 83.82%
CHEMBL220 P22303 Acetylcholinesterase 93.76% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.01% 96.09%
CHEMBL2581 P07339 Cathepsin D 91.53% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 88.21% 94.45%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.35% 89.00%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 85.80% 96.38%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.64% 99.23%
CHEMBL4227 P25090 Lipoxin A4 receptor 84.59% 100.00%
CHEMBL5678 P34947 G protein-coupled receptor kinase 5 84.39% 88.00%
CHEMBL5255 O00206 Toll-like receptor 4 84.21% 92.50%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 83.49% 89.34%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 83.40% 85.00%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 83.37% 94.33%
CHEMBL1781 P11387 DNA topoisomerase I 82.68% 97.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.52% 93.00%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 81.51% 95.71%
CHEMBL340 P08684 Cytochrome P450 3A4 81.22% 91.19%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 80.85% 95.56%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 80.17% 96.00%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 80.15% 95.50%
CHEMBL2072 P35499 Sodium channel protein type IV alpha subunit 80.12% 92.32%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 44445761
LOTUS LTS0190395
wikiData Q105006378