Integerrimide B

Details

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Internal ID 53e9e2b4-a978-4fe9-92b0-9f9cea3a5551
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Oligopeptides
IUPAC Name (3S,6S,9S,12S,15S,18S,21S)-3-(hydroxymethyl)-18-(1H-indol-3-ylmethyl)-15-methyl-9,12-bis(2-methylpropyl)-6-propan-2-yl-1,4,7,10,13,16,19-heptazabicyclo[19.3.0]tetracosane-2,5,8,11,14,17,20-heptone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C39H58N8O8/c1-20(2)15-27-35(51)43-28(16-21(3)4)36(52)46-32(22(5)6)38(54)45-30(19-48)39(55)47-14-10-13-31(47)37(53)44-29(34(50)41-23(7)33(49)42-27)17-24-18-40-26-12-9-8-11-25(24)26/h8-9,11-12,18,20-23,27-32,40,48H,10,13-17,19H2,1-7H3,(H,41,50)(H,42,49)(H,43,51)(H,44,53)(H,45,54)(H,46,52)/t23-,27-,28-,29-,30-,31-,32-/m0/s1
InChI Key WFQBWZPTVRKYLS-HVEPFCGMSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C39H58N8O8
Molecular Weight 766.90 g/mol
Exact Mass 766.43776084 g/mol
Topological Polar Surface Area (TPSA) 231.00 Ų
XlogP 3.40

Synonyms

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CHEMBL447891

2D Structure

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2D Structure of Integerrimide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.77% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.83% 91.11%
CHEMBL333 P08253 Matrix metalloproteinase-2 97.94% 96.31%
CHEMBL5103 Q969S8 Histone deacetylase 10 97.36% 90.08%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.04% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.26% 95.56%
CHEMBL3310 Q96DB2 Histone deacetylase 11 96.01% 88.56%
CHEMBL1937 Q92769 Histone deacetylase 2 95.68% 94.75%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 94.68% 97.64%
CHEMBL3524 P56524 Histone deacetylase 4 93.83% 92.97%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 93.42% 90.71%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.36% 97.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.82% 85.14%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.21% 97.25%
CHEMBL1949 P62937 Cyclophilin A 90.86% 98.57%
CHEMBL321 P14780 Matrix metalloproteinase 9 89.19% 92.12%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.75% 95.89%
CHEMBL228 P31645 Serotonin transporter 86.92% 95.51%
CHEMBL213 P08588 Beta-1 adrenergic receptor 86.76% 95.56%
CHEMBL1951 P21397 Monoamine oxidase A 86.58% 91.49%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.56% 89.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.48% 93.03%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.12% 99.23%
CHEMBL1902 P62942 FK506-binding protein 1A 84.84% 97.05%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 84.50% 95.83%
CHEMBL1978 P11511 Cytochrome P450 19A1 81.68% 91.76%
CHEMBL264 Q9Y5N1 Histamine H3 receptor 81.43% 91.43%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 80.74% 82.38%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Jatropha integerrima

Cross-Links

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PubChem 16059804
LOTUS LTS0203732
wikiData Q105304123