Indocarbazostatin D

Details

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Internal ID ab2968bb-ea11-48b4-8702-547931d1e851
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Carbazoles > Pyrrolocarbazoles > Indolocarbazoles
IUPAC Name methyl (15S,16S,18R)-9-amino-10,16-dihydroxy-15-methyl-3,5-dioxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8(13),9,11,20,22,24,26-nonaene-16-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C27H20N4O7/c1-26-27(36,25(35)37-2)9-14(38-26)30-11-6-4-3-5-10(11)15-18-19(24(34)29-23(18)33)17-16-12(7-8-13(32)20(16)28)31(26)22(17)21(15)30/h3-8,14,32,36H,9,28H2,1-2H3,(H,29,33,34)/t14-,26+,27-/m1/s1
InChI Key DNMMIWFDMTZOGA-SIEABBHJSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C27H20N4O7
Molecular Weight 512.50 g/mol
Exact Mass 512.13319899 g/mol
Topological Polar Surface Area (TPSA) 158.00 Ų
XlogP 1.70

Synonyms

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Methyl (15S,16S,18R)-9-amino-10,16-dihydroxy-15-methyl-3,5-dioxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8(13),9,11,20,22,24,26-nonaene-16-carboxylate

2D Structure

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2D Structure of Indocarbazostatin D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.80% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.44% 85.14%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 99.38% 94.45%
CHEMBL3384 Q16512 Protein kinase N1 98.25% 80.71%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 98.05% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.96% 96.09%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 94.27% 91.79%
CHEMBL2815 P04629 Nerve growth factor receptor Trk-A 92.64% 87.16%
CHEMBL2708 Q16584 Mitogen-activated protein kinase kinase kinase 11 92.18% 81.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.04% 89.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.89% 94.00%
CHEMBL4598 Q13043 Serine/threonine-protein kinase MST1 91.55% 96.64%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.23% 99.23%
CHEMBL5600 P27448 Serine/threonine-protein kinase c-TAK1 91.16% 88.81%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 90.95% 93.03%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 90.54% 83.10%
CHEMBL1163101 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 90.02% 98.11%
CHEMBL4924 Q9UK32 Ribosomal protein S6 kinase alpha 6 89.50% 80.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.29% 97.09%
CHEMBL2581 P07339 Cathepsin D 88.83% 98.95%
CHEMBL2964 P36507 Dual specificity mitogen-activated protein kinase kinase 2 88.71% 80.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.65% 95.89%
CHEMBL340 P08684 Cytochrome P450 3A4 88.09% 91.19%
CHEMBL299 P17252 Protein kinase C alpha 87.85% 98.03%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.50% 86.33%
CHEMBL2801 Q13557 CaM kinase II delta 84.69% 84.49%
CHEMBL4482 O96013 Serine/threonine-protein kinase PAK 4 83.81% 95.42%
CHEMBL5678 P34947 G protein-coupled receptor kinase 5 83.60% 88.00%
CHEMBL221 P23219 Cyclooxygenase-1 82.48% 90.17%
CHEMBL3192 Q9BY41 Histone deacetylase 8 81.24% 93.99%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.16% 97.14%
CHEMBL4208 P20618 Proteasome component C5 81.05% 90.00%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 81.02% 99.15%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 80.56% 85.30%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 80.56% 85.11%
CHEMBL4895 P30530 Tyrosine-protein kinase receptor UFO 80.54% 90.95%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 80.38% 92.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11489129
LOTUS LTS0125602
wikiData Q77566208