Hymenistatin I

Details

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Internal ID d5546c16-cd5b-4a06-8138-992f2707b567
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Oligopeptides
IUPAC Name (1S,7S,10S,13S,19S,22S,25S,28S)-25,28-bis[(2S)-butan-2-yl]-10-[(4-hydroxyphenyl)methyl]-22-(2-methylpropyl)-13-propan-2-yl-3,9,12,15,21,24,27,30-octazatetracyclo[28.3.0.03,7.015,19]tritriacontane-2,8,11,14,20,23,26,29-octone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C47H72N8O9/c1-9-28(7)38-44(61)52-39(29(8)10-2)47(64)55-23-13-16-36(55)45(62)53-21-11-14-34(53)42(59)49-33(25-30-17-19-31(56)20-18-30)41(58)50-37(27(5)6)46(63)54-22-12-15-35(54)43(60)48-32(24-26(3)4)40(57)51-38/h17-20,26-29,32-39,56H,9-16,21-25H2,1-8H3,(H,48,60)(H,49,59)(H,50,58)(H,51,57)(H,52,61)/t28-,29-,32-,33-,34-,35-,36-,37-,38-,39-/m0/s1
InChI Key NACGNHONDBBQGE-MXKYYYADSA-N
Popularity 7 references in papers

Physical and Chemical Properties

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Molecular Formula C47H72N8O9
Molecular Weight 893.10 g/mol
Exact Mass 892.54222590 g/mol
Topological Polar Surface Area (TPSA) 227.00 Ų
XlogP 5.00

Synonyms

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Hymenistatin 1
Hymenistatin I
(1S,7S,10S,13S,19S,22S,25S,28S)-25,28-bis[(2S)-butan-2-yl]-10-[(4-hydroxyphenyl)methyl]-22-(2-methylpropyl)-13-propan-2-yl-3,9,12,15,21,24,27,30-octazatetracyclo[28.3.0.03,7.015,19]tritriacontane-2,8,11,14,20,23,26,29-octone
CHEMBL2370330
DTXSID801045443

2D Structure

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2D Structure of Hymenistatin I

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.82% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.30% 96.09%
CHEMBL5103 Q969S8 Histone deacetylase 10 97.32% 90.08%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.13% 94.45%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 95.32% 90.93%
CHEMBL6175 Q9H3R0 Lysine-specific demethylase 4C 94.15% 96.69%
CHEMBL5608 Q16288 NT-3 growth factor receptor 94.08% 95.89%
CHEMBL1937 Q92769 Histone deacetylase 2 93.94% 94.75%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 93.35% 82.38%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.14% 97.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.08% 85.14%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.93% 97.25%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.64% 95.56%
CHEMBL3524 P56524 Histone deacetylase 4 89.97% 92.97%
CHEMBL5896 O75164 Lysine-specific demethylase 4A 89.81% 99.09%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 89.69% 90.71%
CHEMBL1902 P62942 FK506-binding protein 1A 89.00% 97.05%
CHEMBL4461 Q9NTG7 NAD-dependent deacetylase sirtuin 3 88.57% 94.36%
CHEMBL226 P30542 Adenosine A1 receptor 88.15% 95.93%
CHEMBL4616 Q92847 Ghrelin receptor 87.67% 92.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 87.45% 97.64%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 87.15% 91.11%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 85.72% 93.40%
CHEMBL5203 P33316 dUTP pyrophosphatase 85.25% 99.18%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 84.90% 100.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 84.44% 95.89%
CHEMBL1978 P11511 Cytochrome P450 19A1 81.92% 91.76%
CHEMBL206 P03372 Estrogen receptor alpha 81.82% 97.64%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 81.26% 91.71%
CHEMBL3310 Q96DB2 Histone deacetylase 11 81.04% 88.56%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10102206
LOTUS LTS0135220
wikiData Q105176160