Hydroxyikarugamycin C

Details

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Internal ID 7edaf463-b4fd-44a1-a554-cc8ea1109772
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Monoterpenoids > Iridoids and derivatives
IUPAC Name (3E,5S,7R,8R,10R,11R,12R,13S,14S,15R,16S,18Z,25S)-2,13,14-trihydroxy-11-[(1R)-1-hydroxyethyl]-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1,3,18-triene-20,27,28-trione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C29H40N2O7/c1-13-11-17-18-12-15-8-9-20(33)25-26(35)19(31-29(25)38)6-4-10-30-21(34)7-3-5-16(15)23(18)27(36)28(37)24(17)22(13)14(2)32/h3,7-9,13-19,22-24,27-28,32-33,36-37H,4-6,10-12H2,1-2H3,(H,30,34)(H,31,38)/b7-3-,9-8+,25-20?/t13-,14-,15-,16+,17-,18-,19+,22+,23-,24-,27+,28+/m1/s1
InChI Key RGIYQRIEWZMVCW-NRBUPWTDSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C29H40N2O7
Molecular Weight 528.60 g/mol
Exact Mass 528.28355162 g/mol
Topological Polar Surface Area (TPSA) 156.00 Ų
XlogP 2.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Hydroxyikarugamycin C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.62% 97.25%
CHEMBL2581 P07339 Cathepsin D 98.16% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.93% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.47% 96.09%
CHEMBL1937 Q92769 Histone deacetylase 2 95.45% 94.75%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 94.46% 93.03%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 94.22% 92.88%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.01% 97.09%
CHEMBL5103 Q969S8 Histone deacetylase 10 92.68% 90.08%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 92.40% 96.21%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 90.64% 85.14%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 90.15% 96.77%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 89.65% 91.07%
CHEMBL1994 P08235 Mineralocorticoid receptor 88.93% 100.00%
CHEMBL213 P08588 Beta-1 adrenergic receptor 88.79% 95.56%
CHEMBL226 P30542 Adenosine A1 receptor 88.45% 95.93%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 87.99% 91.03%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.73% 89.00%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 87.14% 82.69%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.91% 90.71%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.25% 94.45%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.40% 99.23%
CHEMBL2535 P11166 Glucose transporter 84.18% 98.75%
CHEMBL1978 P11511 Cytochrome P450 19A1 81.85% 91.76%
CHEMBL3310 Q96DB2 Histone deacetylase 11 81.48% 88.56%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139590316
LOTUS LTS0198070
wikiData Q105235895