Hikiamide A

Details

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Internal ID 5fe19260-3197-489e-a84c-f7cad9c5407a
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name (3R,6R,9R,12R,15R)-3,6-dibenzyl-9,15-bis(2-methylpropyl)-12-propan-2-yl-1,4,7,10,13-pentazacyclopentadecane-2,5,8,11,14-pentone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C35H49N5O5/c1-21(2)17-26-31(41)37-29(20-25-15-11-8-12-16-25)33(43)38-28(19-24-13-9-7-10-14-24)32(42)36-27(18-22(3)4)34(44)40-30(23(5)6)35(45)39-26/h7-16,21-23,26-30H,17-20H2,1-6H3,(H,36,42)(H,37,41)(H,38,43)(H,39,45)(H,40,44)/t26-,27-,28-,29-,30-/m1/s1
InChI Key GYBIEUKVACOKPM-XZTOTZIXSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C35H49N5O5
Molecular Weight 619.80 g/mol
Exact Mass 619.37336968 g/mol
Topological Polar Surface Area (TPSA) 146.00 Ų
XlogP 5.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Hikiamide A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.21% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.22% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.92% 95.56%
CHEMBL4040 P28482 MAP kinase ERK2 92.24% 83.82%
CHEMBL221 P23219 Cyclooxygenase-1 89.17% 90.17%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 88.06% 97.64%
CHEMBL5103 Q969S8 Histone deacetylase 10 85.58% 90.08%
CHEMBL1937 Q92769 Histone deacetylase 2 84.89% 94.75%
CHEMBL1949 P62937 Cyclophilin A 84.10% 98.57%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 82.83% 85.14%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 82.63% 91.11%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 82.48% 96.47%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 82.30% 94.45%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 81.98% 89.67%
CHEMBL3401 O75469 Pregnane X receptor 81.83% 94.73%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.84% 95.50%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 80.66% 94.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139588723
LOTUS LTS0057610
wikiData Q105023515