Herdmanine D

Details

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Internal ID d4ee43a6-01f4-4b4d-b71b-efdbc22eac47
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives > Phenylalanine and derivatives
IUPAC Name (2S)-2-amino-3-[4-(6-bromo-5-hydroxy-1H-indole-3-carbonyl)oxyphenyl]propanoic acid
SMILES (Canonical) C1=CC(=CC=C1CC(C(=O)O)N)OC(=O)C2=CNC3=CC(=C(C=C32)O)Br
SMILES (Isomeric) C1=CC(=CC=C1C[C@@H](C(=O)O)N)OC(=O)C2=CNC3=CC(=C(C=C32)O)Br
InChI InChI=1S/C18H15BrN2O5/c19-13-7-15-11(6-16(13)22)12(8-21-15)18(25)26-10-3-1-9(2-4-10)5-14(20)17(23)24/h1-4,6-8,14,21-22H,5,20H2,(H,23,24)/t14-/m0/s1
InChI Key PKFPVOPFIFUXPW-AWEZNQCLSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C18H15BrN2O5
Molecular Weight 419.20 g/mol
Exact Mass 418.01643 g/mol
Topological Polar Surface Area (TPSA) 126.00 Ų
XlogP 0.50

Synonyms

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CHEBI:69269
(-)-HERDMANINE D
CHEMBL1915724
AT31515
Q27137608
1318852-81-1

2D Structure

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2D Structure of Herdmanine D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.28% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.24% 96.09%
CHEMBL2581 P07339 Cathepsin D 97.17% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.04% 94.45%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 94.81% 99.15%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 92.42% 94.00%
CHEMBL1951 P21397 Monoamine oxidase A 91.88% 91.49%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.87% 95.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 90.80% 99.17%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 89.87% 91.71%
CHEMBL2535 P11166 Glucose transporter 89.70% 98.75%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 89.33% 92.29%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 89.22% 97.21%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 88.21% 82.86%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 86.77% 83.10%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 85.09% 94.62%
CHEMBL3492 P49721 Proteasome Macropain subunit 85.02% 90.24%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.70% 95.89%
CHEMBL4208 P20618 Proteasome component C5 84.28% 90.00%
CHEMBL233 P35372 Mu opioid receptor 83.69% 97.93%
CHEMBL1255126 O15151 Protein Mdm4 81.92% 90.20%
CHEMBL3242 O43570 Carbonic anhydrase XII 81.11% 97.37%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 81.00% 96.95%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.27% 95.50%
CHEMBL3137262 O60341 LSD1/CoREST complex 80.12% 97.09%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 53483957
LOTUS LTS0206824
wikiData Q27137608