Henricine

Details

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Internal ID 9c3ea7de-02ee-4017-af45-a8b1a51b838e
Taxonomy Lignans, neolignans and related compounds > Furanoid lignans > Tetrahydrofuran lignans > 7,7-epoxylignans
IUPAC Name 5-[3,4-dimethyl-5-(3,4,5-trimethoxyphenyl)oxolan-2-yl]-1,3-benzodioxole
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H26O6/c1-12-13(2)21(15-9-18(23-3)22(25-5)19(10-15)24-4)28-20(12)14-6-7-16-17(8-14)27-11-26-16/h6-10,12-13,20-21H,11H2,1-5H3
InChI Key WHNJCTMEGTVMBR-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C22H26O6
Molecular Weight 386.40 g/mol
Exact Mass 386.17293854 g/mol
Topological Polar Surface Area (TPSA) 55.40 Ų
XlogP 4.20

Synonyms

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107783-46-0
HEA78346

2D Structure

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2D Structure of Henricine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.76% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.39% 96.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.43% 86.33%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.73% 85.14%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 91.69% 94.80%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.40% 97.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.44% 95.56%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 88.46% 92.62%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 88.35% 96.77%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 87.97% 97.14%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 87.59% 82.67%
CHEMBL4247 Q9UM73 ALK tyrosine kinase receptor 86.95% 96.86%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.09% 94.45%
CHEMBL4306 P22460 Voltage-gated potassium channel subunit Kv1.5 84.64% 94.03%
CHEMBL4208 P20618 Proteasome component C5 83.59% 90.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 83.58% 93.99%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.35% 94.00%
CHEMBL3438 Q05513 Protein kinase C zeta 82.76% 88.48%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 82.47% 89.62%
CHEMBL2535 P11166 Glucose transporter 82.24% 98.75%
CHEMBL3401 O75469 Pregnane X receptor 81.09% 94.73%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Schisandra henryi

Cross-Links

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PubChem 138108114
LOTUS LTS0184768
wikiData Q105305444