Harmic Acid Methyl Ester

Details

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Internal ID 74a25931-1522-4be5-962c-fd9429535d60
Taxonomy Alkaloids and derivatives > Harmala alkaloids
IUPAC Name methyl 7-methoxy-9H-pyrido[3,4-b]indole-1-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C14H12N2O3/c1-18-8-3-4-9-10-5-6-15-13(14(17)19-2)12(10)16-11(9)7-8/h3-7,16H,1-2H3
InChI Key GGTFWDPYRXONGD-UHFFFAOYSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C14H12N2O3
Molecular Weight 256.26 g/mol
Exact Mass 256.08479225 g/mol
Topological Polar Surface Area (TPSA) 64.20 Ų
XlogP 2.50

Synonyms

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METHYL 7-METHOXY-9H-PYRIDO[3,4-B]INDOLE-1-CARBOXYLATE
methyl 7-methoxy-9H-pyrido(3,4-b)indole-1-carboxylate
Methyl 7-methoxy-9H-pyrido(3,4-b)indole-1-carboxylic acid
Methyl 7-methoxy-9H-pyrido[3,4-b]indole-1-carboxylic acid
RefChem:145269
57498-79-0
CHEMBL1957116
SCHEMBL25294090
DTXSID90725417

2D Structure

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2D Structure of Harmic Acid Methyl Ester

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2292 Q13627 Dual-specificity tyrosine-phosphorylation regulated kinase 1A 98.97% 93.24%
CHEMBL1951 P21397 Monoamine oxidase A 98.39% 91.49%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.35% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.80% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.58% 91.11%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.82% 94.00%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 91.74% 85.30%
CHEMBL1868 P17948 Vascular endothelial growth factor receptor 1 91.66% 96.47%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 91.40% 92.67%
CHEMBL4208 P20618 Proteasome component C5 90.73% 90.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 90.27% 99.17%
CHEMBL2535 P11166 Glucose transporter 88.95% 98.75%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 88.20% 94.80%
CHEMBL1781 P11387 DNA topoisomerase I 87.62% 97.00%
CHEMBL255 P29275 Adenosine A2b receptor 87.14% 98.59%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 85.36% 86.92%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.37% 86.33%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.96% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Banisteriopsis caapi
Trigonostemon bonianus

Cross-Links

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PubChem 57391302
LOTUS LTS0221199
wikiData Q82665897