Hamigeran C

Details

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Internal ID 1d4ef2c7-1508-4b56-87cf-3bc3a5887ea7
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbonyl compounds > Aryl ketones
IUPAC Name [(1R,3aR,4R,10bR)-8-bromo-7-hydroxy-3a,9-dimethyl-5,6-dioxo-1-propan-2-yl-2,3,4,10b-tetrahydro-1H-benzo[e]azulen-4-yl] acetate
SMILES (Canonical) CC1=CC2=C(C(=C1Br)O)C(=O)C(=O)C(C3(C2C(CC3)C(C)C)C)OC(=O)C
SMILES (Isomeric) CC1=CC2=C(C(=C1Br)O)C(=O)C(=O)[C@@H]([C@]3([C@@H]2[C@H](CC3)C(C)C)C)OC(=O)C
InChI InChI=1S/C21H25BrO5/c1-9(2)12-6-7-21(5)15(12)13-8-10(3)16(22)17(24)14(13)18(25)19(26)20(21)27-11(4)23/h8-9,12,15,20,24H,6-7H2,1-5H3/t12-,15-,20+,21-/m1/s1
InChI Key RIFRKOGZXWRBEW-FSKQDFAOSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C21H25BrO5
Molecular Weight 437.30 g/mol
Exact Mass 436.08854 g/mol
Topological Polar Surface Area (TPSA) 80.70 Ų
XlogP 5.20

Synonyms

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CHEMBL480483

2D Structure

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2D Structure of Hamigeran C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.34% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.14% 94.45%
CHEMBL2581 P07339 Cathepsin D 97.38% 98.95%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 94.66% 96.38%
CHEMBL1937 Q92769 Histone deacetylase 2 93.79% 94.75%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.89% 89.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.78% 95.56%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 90.97% 99.15%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.59% 95.89%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.94% 96.09%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 87.12% 93.03%
CHEMBL340 P08684 Cytochrome P450 3A4 87.08% 91.19%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 86.18% 93.40%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.23% 99.23%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.25% 93.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.11% 100.00%
CHEMBL1871 P10275 Androgen Receptor 82.95% 96.43%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 81.98% 93.04%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 81.34% 95.89%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.34% 91.07%
CHEMBL4581 P52732 Kinesin-like protein 1 80.19% 93.18%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.09% 90.08%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 80.07% 96.21%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10320862
LOTUS LTS0077149
wikiData Q105236821