Hamigeran A

Details

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Internal ID 6d2feac5-5a90-4ec7-80a3-9255feb2f397
Taxonomy Benzenoids > Naphthalenes > Naphthalenecarboxylic acids and derivatives > Naphthalenecarboxylic acids
IUPAC Name methyl (1R,3aR,4R,9bR)-7-bromo-4,6-dihydroxy-3a,8-dimethyl-5-oxo-1-propan-2-yl-1,2,3,9b-tetrahydrocyclopenta[a]naphthalene-4-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H25BrO5/c1-9(2)11-6-7-19(4)14(11)12-8-10(3)15(21)16(22)13(12)17(23)20(19,25)18(24)26-5/h8-9,11,14,22,25H,6-7H2,1-5H3/t11-,14-,19-,20-/m1/s1
InChI Key ZUMYUUHSQZYLPD-VKUYIICUSA-N
Popularity 8 references in papers

Physical and Chemical Properties

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Molecular Formula C20H25BrO5
Molecular Weight 425.30 g/mol
Exact Mass 424.08854 g/mol
Topological Polar Surface Area (TPSA) 83.80 Ų
XlogP 5.00

Synonyms

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CHEMBL364659
DTXSID701043701
255882-01-0
Q59315549
7-bromo-4beta,6-dihydro-1beta-isopropyl-4alpha-methoxycarbonyl-3aalpha,8- dimethylcyclopenta[a-1a,3a,4,5-tetrahydronaphthalen-5-one]

2D Structure

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2D Structure of Hamigeran A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.58% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.14% 94.45%
CHEMBL2581 P07339 Cathepsin D 95.93% 98.95%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 93.25% 91.07%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 91.34% 96.38%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 90.84% 93.03%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.81% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.76% 95.56%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 90.71% 99.15%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.76% 95.89%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 89.11% 95.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.11% 97.09%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 87.04% 93.00%
CHEMBL340 P08684 Cytochrome P450 3A4 86.80% 91.19%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.31% 90.71%
CHEMBL1871 P10275 Androgen Receptor 84.72% 96.43%
CHEMBL4208 P20618 Proteasome component C5 84.04% 90.00%
CHEMBL3975 P09467 Fructose-1,6-bisphosphatase 83.64% 92.95%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 83.52% 96.21%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.40% 99.23%
CHEMBL4302 P08183 P-glycoprotein 1 83.20% 92.98%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 82.89% 91.03%
CHEMBL2535 P11166 Glucose transporter 82.74% 98.75%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.73% 94.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.62% 92.62%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 81.98% 91.24%
CHEMBL5028 O14672 ADAM10 81.34% 97.50%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 80.86% 92.88%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.18% 96.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10025421
LOTUS LTS0084651
wikiData Q59315549