(6aR)-6,6a,9,10-Tetrahydro-2H,8H-(1,3)oxazino(3,2-a)pyrrolo(4,3,2-de)quinoline-2,3(4H)-dione

Details

Top
Internal ID bf6ad7b2-b622-4f9e-8c93-eb6ad48eef20
Taxonomy Organoheterocyclic compounds > Quinolines and derivatives > Pyrroloquinolines > Pyrrolo[4,3,2-de]quinolines
IUPAC Name (7R)-6-oxa-2,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1(15),9,12(16)-triene-13,14-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C13H12N2O3/c16-9-5-8-11-7(6-14-12(11)13(9)17)4-10-15(8)2-1-3-18-10/h5-6,10,14H,1-4H2/t10-/m1/s1
InChI Key GTVMGUBGOSWMOJ-SNVBAGLBSA-N
Popularity 4 references in papers

Physical and Chemical Properties

Top
Molecular Formula C13H12N2O3
Molecular Weight 244.25 g/mol
Exact Mass 244.08479225 g/mol
Topological Polar Surface Area (TPSA) 62.40 Ų
XlogP 0.60

Synonyms

Top
151964-21-5
838N74Y28P
(6aR)-6,6a,9,10-Tetrahydro-2H,8H-(1,3)oxazino(3,2-a)pyrrolo(4,3,2-de)quinoline-2,3(4H)-dione
RefChem:1050668
6-oxa-2,11-diazatetracyclo(7.6.1.0^(2,7).0^(12,16))hexadeca-1(15),9,12(16)-triene-13,14-dione
(7R)-6-oxa-2,11-diazatetracyclo(7.6.1.02,7.012,16)hexadeca-1(15),9,12(16)-triene-13,14-dione
UNII-838N74Y28P
2H,8H-(1,3)Oxazino(3,2-a)pyrrolo(4,3,2-de)quinoline-2,3(4H)-dione, 6,6a,9,10-tetrahydro-, (R)-
Haematopodine
orb2813854
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

Top
2D Structure of (6aR)-6,6a,9,10-Tetrahydro-2H,8H-(1,3)oxazino(3,2-a)pyrrolo(4,3,2-de)quinoline-2,3(4H)-dione

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 96.24% 98.95%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 93.68% 93.40%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.96% 85.14%
CHEMBL3192 Q9BY41 Histone deacetylase 8 91.43% 93.99%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.24% 94.45%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.65% 89.00%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 90.20% 96.00%
CHEMBL3384 Q16512 Protein kinase N1 90.14% 80.71%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.69% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.52% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.37% 91.11%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 89.27% 93.03%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.19% 97.09%
CHEMBL255 P29275 Adenosine A2b receptor 88.54% 98.59%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 88.42% 93.04%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.32% 95.89%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 88.17% 80.96%
CHEMBL2708 Q16584 Mitogen-activated protein kinase kinase kinase 11 85.06% 81.14%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 84.85% 96.39%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 84.31% 96.67%
CHEMBL217 P14416 Dopamine D2 receptor 84.10% 95.62%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.59% 99.23%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.21% 100.00%
CHEMBL4588 P22894 Matrix metalloproteinase 8 81.96% 94.66%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 81.33% 83.10%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 81.27% 94.00%
CHEMBL333 P08253 Matrix metalloproteinase-2 81.07% 96.31%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.55% 90.08%
CHEMBL1978 P11511 Cytochrome P450 19A1 80.44% 91.76%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 15286692
LOTUS LTS0080476
wikiData Q5638217