H-Ile-Tyr-Glu-Pro-Glu-Ile-Ala-NH2

Details

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Internal ID f4f89f92-e273-4be3-b5fd-14375326d702
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides
IUPAC Name (4S)-4-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-carboxybutanoyl]pyrrolidine-2-carbonyl]amino]-5-[[(2S,3S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
SMILES (Canonical) CCC(C)C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)O)C(=O)N2CCCC2C(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)N)N
SMILES (Isomeric) CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N)N
InChI InChI=1S/C39H60N8O12/c1-6-20(3)31(40)37(57)45-27(19-23-10-12-24(48)13-11-23)35(55)44-26(15-17-30(51)52)39(59)47-18-8-9-28(47)36(56)43-25(14-16-29(49)50)34(54)46-32(21(4)7-2)38(58)42-22(5)33(41)53/h10-13,20-22,25-28,31-32,48H,6-9,14-19,40H2,1-5H3,(H2,41,53)(H,42,58)(H,43,56)(H,44,55)(H,45,57)(H,46,54)(H,49,50)(H,51,52)/t20-,21-,22-,25-,26-,27-,28-,31-,32-/m0/s1
InChI Key VTTWVWCMIXBJDI-ZBKHOHQESA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C39H60N8O12
Molecular Weight 832.90 g/mol
Exact Mass 832.43306938 g/mol
Topological Polar Surface Area (TPSA) 330.00 Ų
XlogP -2.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of H-Ile-Tyr-Glu-Pro-Glu-Ile-Ala-NH2

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.86% 98.95%
CHEMBL2514 O95665 Neurotensin receptor 2 99.25% 100.00%
CHEMBL4123 P30989 Neurotensin receptor 1 98.76% 96.67%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.61% 96.09%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 97.68% 98.33%
CHEMBL3837 P07711 Cathepsin L 97.42% 96.61%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 96.53% 97.64%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 96.47% 96.67%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 96.35% 97.23%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 96.01% 100.00%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 95.98% 93.10%
CHEMBL340 P08684 Cytochrome P450 3A4 95.00% 91.19%
CHEMBL230 P35354 Cyclooxygenase-2 93.92% 89.63%
CHEMBL3359 P21462 Formyl peptide receptor 1 93.84% 93.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.62% 97.09%
CHEMBL1255126 O15151 Protein Mdm4 93.26% 90.20%
CHEMBL5608 Q16288 NT-3 growth factor receptor 92.83% 95.89%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 91.61% 98.24%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 91.33% 96.03%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 91.15% 90.71%
CHEMBL3060 Q9Y345 Glycine transporter 2 90.76% 99.17%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 90.29% 93.00%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 90.20% 91.81%
CHEMBL4227 P25090 Lipoxin A4 receptor 89.37% 100.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.27% 95.56%
CHEMBL206 P03372 Estrogen receptor alpha 88.11% 97.64%
CHEMBL259 P32245 Melanocortin receptor 4 87.91% 95.38%
CHEMBL221 P23219 Cyclooxygenase-1 87.85% 90.17%
CHEMBL3024 P53350 Serine/threonine-protein kinase PLK1 87.37% 97.43%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 87.21% 98.94%
CHEMBL2319 P06870 Kallikrein 1 86.56% 90.95%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 85.85% 82.69%
CHEMBL2073 P07947 Tyrosine-protein kinase YES 85.72% 83.14%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.41% 97.14%
CHEMBL4198 P98170 Inhibitor of apoptosis protein 3 85.31% 97.79%
CHEMBL249 P25103 Neurokinin 1 receptor 85.26% 99.17%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 84.83% 95.89%
CHEMBL236 P41143 Delta opioid receptor 84.16% 99.35%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 83.95% 100.00%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 83.63% 82.38%
CHEMBL1873 P00750 Tissue-type plasminogen activator 83.48% 93.33%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 83.41% 100.00%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 82.75% 85.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 82.21% 94.45%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 82.10% 95.00%
CHEMBL4330 Q9NS75 Cysteinyl leukotriene receptor 2 81.25% 98.00%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 80.45% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 163185874
LOTUS LTS0086030
wikiData Q105293008