H-DL-Trp-DL-Leu-DL-Val-DL-xiThr-bAib-DL-Leu-DL-Leu-DL-Ala-DL-Val-DL-Ala-OH

Details

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Internal ID 71b06b04-e069-49ce-a069-003da921ef5f
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name 2-[[2-[2-[[2-[[2-[[3-[[2-[[2-[[2-[[2-amino-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-2-methylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]propanoylamino]-3-methylbutanoyl]amino]propanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C53H87N11O12/c1-25(2)19-38(47(69)57-31(12)45(67)62-41(28(7)8)51(73)58-32(13)53(75)76)61-48(70)39(20-26(3)4)59-44(66)30(11)23-56-50(72)43(33(14)65)64-52(74)42(29(9)10)63-49(71)40(21-27(5)6)60-46(68)36(54)22-34-24-55-37-18-16-15-17-35(34)37/h15-18,24-33,36,38-43,55,65H,19-23,54H2,1-14H3,(H,56,72)(H,57,69)(H,58,73)(H,59,66)(H,60,68)(H,61,70)(H,62,67)(H,63,71)(H,64,74)(H,75,76)
InChI Key YAGDDBBKSNUSSG-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C53H87N11O12
Molecular Weight 1070.30 g/mol
Exact Mass 1069.65356725 g/mol
Topological Polar Surface Area (TPSA) 361.00 Ų
XlogP 0.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of H-DL-Trp-DL-Leu-DL-Val-DL-xiThr-bAib-DL-Leu-DL-Leu-DL-Ala-DL-Val-DL-Ala-OH

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.78% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.94% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.56% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 96.78% 90.17%
CHEMBL3837 P07711 Cathepsin L 96.58% 96.61%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.28% 95.56%
CHEMBL1255126 O15151 Protein Mdm4 94.03% 90.20%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 92.97% 100.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 92.50% 93.56%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 91.83% 83.10%
CHEMBL4040 P28482 MAP kinase ERK2 91.59% 83.82%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 91.06% 98.33%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 90.70% 97.23%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 89.74% 96.00%
CHEMBL3308 P55212 Caspase-6 89.59% 97.56%
CHEMBL213 P08588 Beta-1 adrenergic receptor 88.51% 95.56%
CHEMBL2095164 P49354 Geranylgeranyl transferase type I 88.32% 92.80%
CHEMBL222 P23975 Norepinephrine transporter 86.73% 96.06%
CHEMBL2431 P31751 Serine/threonine-protein kinase AKT2 86.68% 98.33%
CHEMBL3492 P49721 Proteasome Macropain subunit 86.65% 90.24%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 85.82% 92.29%
CHEMBL5028 O14672 ADAM10 85.45% 97.50%
CHEMBL2535 P11166 Glucose transporter 85.26% 98.75%
CHEMBL3310 Q96DB2 Histone deacetylase 11 84.75% 88.56%
CHEMBL3776 Q14790 Caspase-8 83.53% 97.06%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.38% 97.09%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.91% 100.00%
CHEMBL1287628 Q9Y5S8 NADPH oxidase 1 82.51% 95.48%
CHEMBL4816 Q9Y243 Serine/threonine-protein kinase AKT3 81.99% 96.28%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 81.40% 89.62%
CHEMBL3176 O43603 Galanin receptor 2 81.13% 98.89%
CHEMBL230 P35354 Cyclooxygenase-2 81.09% 89.63%
CHEMBL2514 O95665 Neurotensin receptor 2 80.10% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 162815578
LOTUS LTS0074697
wikiData Q104201509