H-DL-Pyr-DL-Ala-DL-Asp-DL-Pro-DL-Asn-DL-Ala-DL-Phe-DL-Tyr-Gly-DL-Leu-DL-Met-NH2

Details

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Internal ID 9f06b43f-7635-458c-b1eb-262c9bf11e14
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name 4-[2-[[4-amino-1-[[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-oxo-3-[2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoylamino]butanoic acid
SMILES (Canonical) CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C4CCC(=O)N4
SMILES (Isomeric) CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C3CCCN3C(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C4CCC(=O)N4
InChI InChI=1S/C55H77N13O16S/c1-28(2)22-36(52(81)63-34(46(57)75)19-21-85-5)62-44(72)27-58-49(78)37(24-32-13-15-33(69)16-14-32)65-53(82)38(23-31-10-7-6-8-11-31)64-47(76)29(3)60-51(80)39(25-42(56)70)66-54(83)41-12-9-20-68(41)55(84)40(26-45(73)74)67-48(77)30(4)59-50(79)35-17-18-43(71)61-35/h6-8,10-11,13-16,28-30,34-41,69H,9,12,17-27H2,1-5H3,(H2,56,70)(H2,57,75)(H,58,78)(H,59,79)(H,60,80)(H,61,71)(H,62,72)(H,63,81)(H,64,76)(H,65,82)(H,66,83)(H,67,77)(H,73,74)
InChI Key HRAACOKBZHCXOF-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C55H77N13O16S
Molecular Weight 1208.30 g/mol
Exact Mass 1207.53319459 g/mol
Topological Polar Surface Area (TPSA) 480.00 Ų
XlogP -1.60

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of H-DL-Pyr-DL-Ala-DL-Asp-DL-Pro-DL-Asn-DL-Ala-DL-Phe-DL-Tyr-Gly-DL-Leu-DL-Met-NH2

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.99% 98.95%
CHEMBL230 P35354 Cyclooxygenase-2 99.89% 89.63%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 99.38% 97.64%
CHEMBL236 P41143 Delta opioid receptor 98.60% 99.35%
CHEMBL1255126 O15151 Protein Mdm4 98.47% 90.20%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 98.26% 97.23%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.93% 96.09%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 97.85% 96.67%
CHEMBL2514 O95665 Neurotensin receptor 2 97.50% 100.00%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 97.49% 98.33%
CHEMBL221 P23219 Cyclooxygenase-1 96.74% 90.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.45% 91.11%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 96.32% 100.00%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 96.18% 98.24%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 96.15% 93.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 96.05% 97.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.91% 97.09%
CHEMBL259 P32245 Melanocortin receptor 4 95.47% 95.38%
CHEMBL4361 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 95.30% 95.52%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.04% 95.56%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 94.98% 82.69%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 94.31% 90.71%
CHEMBL3359 P21462 Formyl peptide receptor 1 94.22% 93.56%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 94.12% 91.81%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 93.64% 100.00%
CHEMBL4123 P30989 Neurotensin receptor 1 93.62% 96.67%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.19% 94.45%
CHEMBL237 P41145 Kappa opioid receptor 93.00% 98.10%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 92.87% 96.03%
CHEMBL5103 Q969S8 Histone deacetylase 10 92.66% 90.08%
CHEMBL4040 P28482 MAP kinase ERK2 91.99% 83.82%
CHEMBL340 P08684 Cytochrome P450 3A4 91.89% 91.19%
CHEMBL3060 Q9Y345 Glycine transporter 2 91.60% 99.17%
CHEMBL3176 O43603 Galanin receptor 2 90.30% 98.89%
CHEMBL2535 P11166 Glucose transporter 89.69% 98.75%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 89.61% 93.10%
CHEMBL4801 P29466 Caspase-1 89.43% 96.85%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 89.11% 96.67%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 88.82% 82.38%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 88.54% 95.89%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 87.73% 96.47%
CHEMBL249 P25103 Neurokinin 1 receptor 87.58% 99.17%
CHEMBL4588 P22894 Matrix metalloproteinase 8 86.91% 94.66%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 86.01% 90.93%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.01% 95.89%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 85.32% 85.00%
CHEMBL4644 P41968 Melanocortin receptor 3 85.16% 99.52%
CHEMBL2803 P43403 Tyrosine-protein kinase ZAP-70 85.07% 82.50%
CHEMBL2095164 P49354 Geranylgeranyl transferase type I 84.95% 92.80%
CHEMBL1873 P00750 Tissue-type plasminogen activator 84.72% 93.33%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 83.34% 88.42%
CHEMBL3310 Q96DB2 Histone deacetylase 11 82.59% 88.56%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 82.16% 99.15%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 82.14% 98.94%
CHEMBL4227 P25090 Lipoxin A4 receptor 81.39% 100.00%
CHEMBL2073 P07947 Tyrosine-protein kinase YES 81.19% 83.14%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.08% 96.00%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 80.75% 95.00%
CHEMBL1921 P47901 Vasopressin V1b receptor 80.50% 92.50%
CHEMBL4625 Q07817 Apoptosis regulator Bcl-X 80.25% 99.77%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 85118837
LOTUS LTS0224053
wikiData Q105032534