H-DL-Pyr-Asn-Pro-DL-Asn-Arg-Phe-Ile-Gly-Leu-Met-NH2

Details

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Internal ID d6b4a938-f9c3-4812-9688-d815148d9e2b
Taxonomy Organic Polymers > Polypeptides
IUPAC Name N-[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-1-[(2S)-4-amino-4-oxo-2-[(5-oxopyrrolidine-2-carbonyl)amino]butanoyl]pyrrolidine-2-carbonyl]amino]butanediamide
SMILES (Canonical) CCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)N)NC(=O)C2CCCN2C(=O)C(CC(=O)N)NC(=O)C3CCC(=O)N3
SMILES (Isomeric) CC[C@H](C)[C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)C(CC(=O)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(=O)N)NC(=O)C3CCC(=O)N3
InChI InChI=1S/C52H82N16O13S/c1-6-28(4)42(50(80)59-26-41(72)61-33(22-27(2)3)46(76)62-30(43(55)73)18-21-82-5)67-48(78)34(23-29-12-8-7-9-13-29)64-44(74)31(14-10-19-58-52(56)57)63-47(77)35(24-38(53)69)65-49(79)37-15-11-20-68(37)51(81)36(25-39(54)70)66-45(75)32-16-17-40(71)60-32/h7-9,12-13,27-28,30-37,42H,6,10-11,14-26H2,1-5H3,(H2,53,69)(H2,54,70)(H2,55,73)(H,59,80)(H,60,71)(H,61,72)(H,62,76)(H,63,77)(H,64,74)(H,65,79)(H,66,75)(H,67,78)(H4,56,57,58)/t28-,30-,31-,32?,33-,34-,35?,36-,37-,42-/m0/s1
InChI Key GGIXGYYACCFXOQ-SDSVEIOUSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C52H82N16O13S
Molecular Weight 1171.40 g/mol
Exact Mass 1170.59679791 g/mol
Topological Polar Surface Area (TPSA) 501.00 Ų
XlogP -3.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of H-DL-Pyr-Asn-Pro-DL-Asn-Arg-Phe-Ile-Gly-Leu-Met-NH2

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.99% 98.95%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 99.62% 98.33%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 99.44% 97.64%
CHEMBL230 P35354 Cyclooxygenase-2 99.36% 89.63%
CHEMBL4361 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 99.06% 95.52%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.84% 96.09%
CHEMBL204 P00734 Thrombin 98.68% 96.01%
CHEMBL2514 O95665 Neurotensin receptor 2 98.65% 100.00%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 98.31% 96.67%
CHEMBL4123 P30989 Neurotensin receptor 1 97.71% 96.67%
CHEMBL4588 P22894 Matrix metalloproteinase 8 97.65% 94.66%
CHEMBL259 P32245 Melanocortin receptor 4 97.31% 95.38%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 97.13% 91.81%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 96.12% 98.24%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 96.06% 88.42%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 95.87% 93.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.76% 97.09%
CHEMBL3359 P21462 Formyl peptide receptor 1 95.74% 93.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 95.59% 90.71%
CHEMBL3837 P07711 Cathepsin L 95.46% 96.61%
CHEMBL237 P41145 Kappa opioid receptor 95.35% 98.10%
CHEMBL1255126 O15151 Protein Mdm4 95.01% 90.20%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 94.76% 98.94%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.75% 95.56%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 94.59% 100.00%
CHEMBL4644 P41968 Melanocortin receptor 3 94.10% 99.52%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.80% 91.11%
CHEMBL221 P23219 Cyclooxygenase-1 93.71% 90.17%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 93.64% 97.14%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 92.88% 96.47%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.75% 94.45%
CHEMBL3060 Q9Y345 Glycine transporter 2 92.16% 99.17%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 92.03% 82.69%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 91.39% 97.50%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 91.31% 93.03%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 91.22% 100.00%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 90.81% 97.23%
CHEMBL340 P08684 Cytochrome P450 3A4 90.22% 91.19%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 89.39% 96.00%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 89.24% 96.03%
CHEMBL2535 P11166 Glucose transporter 89.12% 98.75%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 88.66% 95.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 87.84% 90.08%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 86.81% 96.67%
CHEMBL2803 P43403 Tyrosine-protein kinase ZAP-70 86.75% 82.50%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.94% 95.89%
CHEMBL4608 P33032 Melanocortin receptor 5 85.27% 97.00%
CHEMBL4227 P25090 Lipoxin A4 receptor 84.88% 100.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 84.70% 95.89%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 84.52% 82.38%
CHEMBL4462 Q8IXJ6 NAD-dependent deacetylase sirtuin 2 84.36% 90.24%
CHEMBL236 P41143 Delta opioid receptor 84.24% 99.35%
CHEMBL5028 O14672 ADAM10 83.99% 97.50%
CHEMBL4801 P29466 Caspase-1 83.85% 96.85%
CHEMBL2327 P21452 Neurokinin 2 receptor 83.78% 98.89%
CHEMBL4461 Q9NTG7 NAD-dependent deacetylase sirtuin 3 82.57% 94.36%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 82.28% 90.24%
CHEMBL3729 P22748 Carbonic anhydrase IV 81.56% 99.23%
CHEMBL255 P29275 Adenosine A2b receptor 81.53% 98.59%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 81.29% 96.25%
CHEMBL3310 Q96DB2 Histone deacetylase 11 81.28% 88.56%
CHEMBL4625 Q07817 Apoptosis regulator Bcl-X 81.18% 99.77%
CHEMBL3024 P53350 Serine/threonine-protein kinase PLK1 81.08% 97.43%
CHEMBL3176 O43603 Galanin receptor 2 81.02% 98.89%
CHEMBL4208 P20618 Proteasome component C5 80.02% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 168489
LOTUS LTS0137606
wikiData Q105106844