H-bAla(2R-OH,3R-Bn)-Val-Pro-D-Pro-OH

Details

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Internal ID 57e9a336-b369-4180-80e7-646482a9fdde
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (2R)-1-[(2S)-1-[(2S)-2-[[(2R,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
SMILES (Canonical) CC(C)C(C(=O)N1CCCC1C(=O)N2CCCC2C(=O)O)NC(=O)C(C(CC3=CC=CC=C3)N)O
SMILES (Isomeric) CC(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)N2CCC[C@@H]2C(=O)O)NC(=O)[C@@H]([C@@H](CC3=CC=CC=C3)N)O
InChI InChI=1S/C25H36N4O6/c1-15(2)20(27-22(31)21(30)17(26)14-16-8-4-3-5-9-16)24(33)28-12-6-10-18(28)23(32)29-13-7-11-19(29)25(34)35/h3-5,8-9,15,17-21,30H,6-7,10-14,26H2,1-2H3,(H,27,31)(H,34,35)/t17-,18+,19-,20+,21-/m1/s1
InChI Key ZLNGLBIUHZXFQA-VIYGXFRKSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C25H36N4O6
Molecular Weight 488.60 g/mol
Exact Mass 488.26348488 g/mol
Topological Polar Surface Area (TPSA) 153.00 Ų
XlogP -1.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of H-bAla(2R-OH,3R-Bn)-Val-Pro-D-Pro-OH

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.48% 98.95%
CHEMBL221 P23219 Cyclooxygenase-1 96.95% 90.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.30% 96.09%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 95.74% 98.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.08% 95.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.60% 95.89%
CHEMBL2514 O95665 Neurotensin receptor 2 89.68% 100.00%
CHEMBL4040 P28482 MAP kinase ERK2 89.39% 83.82%
CHEMBL3202 P48147 Prolyl endopeptidase 89.10% 90.65%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 88.65% 98.24%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 87.17% 97.64%
CHEMBL4072 P07858 Cathepsin B 85.88% 93.67%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.67% 90.71%
CHEMBL4208 P20618 Proteasome component C5 85.25% 90.00%
CHEMBL1907599 P05556 Integrin alpha-4/beta-1 85.04% 92.86%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 84.96% 95.89%
CHEMBL5028 O14672 ADAM10 84.91% 97.50%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.92% 94.45%
CHEMBL4227 P25090 Lipoxin A4 receptor 83.85% 100.00%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 82.92% 100.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.62% 97.09%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 82.14% 96.03%
CHEMBL4393 P39900 Matrix metalloproteinase 12 82.03% 92.22%
CHEMBL3492 P49721 Proteasome Macropain subunit 81.83% 90.24%
CHEMBL230 P35354 Cyclooxygenase-2 81.78% 89.63%
CHEMBL3359 P21462 Formyl peptide receptor 1 81.48% 93.56%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.47% 93.03%
CHEMBL1907 P15144 Aminopeptidase N 81.01% 93.31%
CHEMBL2327 P21452 Neurokinin 2 receptor 80.64% 98.89%
CHEMBL3384 Q16512 Protein kinase N1 80.55% 80.71%
CHEMBL253 P34972 Cannabinoid CB2 receptor 80.46% 97.25%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 163009867
LOTUS LTS0128790
wikiData Q105378993