Guineamide F

Details

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Internal ID fd363c93-2f91-4032-865e-8726d0015359
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (3S,6S,16S,19S)-3,16-dibenzyl-4,9,9,17-tetramethyl-6-propan-2-yl-10-propyl-11-oxa-1,4,7,14,17-pentazabicyclo[17.3.0]docosane-2,5,8,12,15,18-hexone
SMILES (Canonical) CCCC1C(C(=O)NC(C(=O)N(C(C(=O)N2CCCC2C(=O)N(C(C(=O)NCC(=O)O1)CC3=CC=CC=C3)C)CC4=CC=CC=C4)C)C(C)C)(C)C
SMILES (Isomeric) CCCC1C(C(=O)N[C@H](C(=O)N([C@H](C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)NCC(=O)O1)CC3=CC=CC=C3)C)CC4=CC=CC=C4)C)C(C)C)(C)C
InChI InChI=1S/C40H55N5O7/c1-8-16-32-40(4,5)39(51)42-34(26(2)3)38(50)44(7)31(24-28-19-13-10-14-20-28)37(49)45-22-15-21-29(45)36(48)43(6)30(23-27-17-11-9-12-18-27)35(47)41-25-33(46)52-32/h9-14,17-20,26,29-32,34H,8,15-16,21-25H2,1-7H3,(H,41,47)(H,42,51)/t29-,30-,31-,32?,34-/m0/s1
InChI Key HGABVVDKSKHSGK-AILSMDFESA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C40H55N5O7
Molecular Weight 717.90 g/mol
Exact Mass 717.41014911 g/mol
Topological Polar Surface Area (TPSA) 145.00 Ų
XlogP 5.20

Synonyms

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560082-15-7
DTXSID901046070

2D Structure

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2D Structure of Guineamide F

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.77% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 98.46% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.91% 96.09%
CHEMBL5103 Q969S8 Histone deacetylase 10 94.63% 90.08%
CHEMBL221 P23219 Cyclooxygenase-1 94.51% 90.17%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.82% 95.56%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 93.56% 97.64%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.47% 94.45%
CHEMBL333 P08253 Matrix metalloproteinase-2 92.54% 96.31%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.52% 95.89%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 91.21% 82.38%
CHEMBL1902 P62942 FK506-binding protein 1A 90.95% 97.05%
CHEMBL3202 P48147 Prolyl endopeptidase 89.62% 90.65%
CHEMBL253 P34972 Cannabinoid CB2 receptor 88.47% 97.25%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 86.44% 93.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 85.53% 86.33%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.63% 99.23%
CHEMBL3310 Q96DB2 Histone deacetylase 11 83.71% 88.56%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.58% 97.14%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.36% 93.03%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 82.52% 91.11%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.88% 89.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10930574
LOTUS LTS0116243
wikiData Q75057137