Grossularine 1

Details

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Internal ID 6f28a4c5-17e1-4bcb-abbc-45eeb90712b4
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Indolecarboxylic acids and derivatives
IUPAC Name [10-amino-14-(dimethylamino)-8,13,15-triazatetracyclo[7.6.0.02,7.011,15]pentadeca-1,3,5,7,9,11,13-heptaen-12-yl]-(1H-indol-3-yl)methanone
SMILES (Canonical) CN(C)C1=NC(=C2N1C3=C4C=CC=CC4=NC3=C2N)C(=O)C5=CNC6=CC=CC=C65
SMILES (Isomeric) CN(C)C1=NC(=C2N1C3=C4C=CC=CC4=NC3=C2N)C(=O)C5=CNC6=CC=CC=C65
InChI InChI=1S/C23H18N6O/c1-28(2)23-27-19(22(30)14-11-25-15-9-5-3-7-12(14)15)21-17(24)18-20(29(21)23)13-8-4-6-10-16(13)26-18/h3-11,25H,24H2,1-2H3
InChI Key FCNJUPUMHGDABC-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C23H18N6O
Molecular Weight 394.40 g/mol
Exact Mass 394.15420922 g/mol
Topological Polar Surface Area (TPSA) 92.30 Ų
XlogP 4.10

Synonyms

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94935-97-4
[10-amino-14-(dimethylamino)-8,13,15-triazatetracyclo[7.6.0.02,7.011,15]pentadeca-1,3,5,7,9,11,13-heptaen-12-yl]-(1H-indol-3-yl)methanone
Grossularine-1
DTXSID70915213
[4-Amino-1-(dimethylamino)imidazo[1',5':1,5]pyrrolo[3,2-b]indol-3-yl](1H-indol-3-yl)methanone
Methanone, (3-(dimethylamino)-9,10-dihydro-10-iminoimidazo(1',5':1,5)pyrrolo(3,2-b)indol-1-yl)-1H-indol-3-yl-

2D Structure

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2D Structure of Grossularine 1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.13% 96.09%
CHEMBL2581 P07339 Cathepsin D 95.46% 98.95%
CHEMBL221 P23219 Cyclooxygenase-1 94.86% 90.17%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.48% 94.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.52% 95.56%
CHEMBL3959 P16083 Quinone reductase 2 89.71% 89.49%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.13% 99.23%
CHEMBL4040 P28482 MAP kinase ERK2 85.85% 83.82%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 85.10% 96.67%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.93% 93.03%
CHEMBL2535 P11166 Glucose transporter 81.70% 98.75%
CHEMBL3384 Q16512 Protein kinase N1 81.66% 80.71%
CHEMBL1287628 Q9Y5S8 NADPH oxidase 1 80.92% 95.48%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 80.87% 91.11%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 80.55% 93.65%
CHEMBL1868 P17948 Vascular endothelial growth factor receptor 1 80.47% 96.47%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 80.14% 93.10%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146866
LOTUS LTS0133324
wikiData Q82886130