Granaxylocarpin E

Details

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Internal ID d8a5cf11-5a4d-41dd-a4bf-904f5303a6e7
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Triterpenoids > Limonoids
IUPAC Name methyl (2R)-2-acetyloxy-2-[(1S,2R,5R,6R,10R,11S,12R,13R,14R,15S,17S,18S)-12,14,17-triacetyloxy-6-(furan-3-yl)-11-hydroxy-1,5,15-trimethyl-8-oxo-7-oxapentacyclo[13.2.1.02,11.05,10.013,17]octadecan-18-yl]acetate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C35H44O14/c1-16(36)45-25(30(41)43-8)26-32(6)15-34(49-19(4)39)24(28(32)46-17(2)37)29(47-18(3)38)35(42)21(33(26,34)7)9-11-31(5)22(35)13-23(40)48-27(31)20-10-12-44-14-20/h10,12,14,21-22,24-29,42H,9,11,13,15H2,1-8H3/t21-,22-,24-,25-,26+,27+,28-,29-,31-,32+,33-,34+,35-/m1/s1
InChI Key MODWWVKERCVJOU-QHXFVWPSSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C35H44O14
Molecular Weight 688.70 g/mol
Exact Mass 688.27310607 g/mol
Topological Polar Surface Area (TPSA) 191.00 Ų
XlogP 2.30

Synonyms

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CHEMBL388296

2D Structure

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2D Structure of Granaxylocarpin E

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.75% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.61% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.47% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 94.82% 85.14%
CHEMBL2996 Q05655 Protein kinase C delta 94.09% 97.79%
CHEMBL2581 P07339 Cathepsin D 93.44% 98.95%
CHEMBL221 P23219 Cyclooxygenase-1 92.91% 90.17%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.96% 97.25%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.46% 89.00%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 89.96% 91.24%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 88.13% 82.69%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.41% 97.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.08% 95.89%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.81% 86.33%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 86.27% 95.71%
CHEMBL340 P08684 Cytochrome P450 3A4 85.72% 91.19%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 85.17% 93.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 84.83% 92.62%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.46% 97.14%
CHEMBL5028 O14672 ADAM10 83.77% 97.50%
CHEMBL4040 P28482 MAP kinase ERK2 83.11% 83.82%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.06% 99.23%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 81.03% 94.00%
CHEMBL299 P17252 Protein kinase C alpha 80.76% 98.03%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 80.61% 94.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.51% 93.03%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Xylocarpus granatum

Cross-Links

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PubChem 16216669
LOTUS LTS0074710
wikiData Q105168815