Glycyl-L-tyrosine

Details

• Internal ID: 4e33094e-19cd-4c57-9142-13b5cd01e4b9
• Taxonomy: Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides
• IUPAC Name: (2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoic acid
• SMILES (Canonical): C1=CC(=CC=C1CC(C(=O)O)NC(=O)CN)O
• SMILES (Isomeric): C1=CC(=CC=C1C[C@@H](C(=O)O)NC(=O)CN)O
• InChI: InChI=1S/C11H14N2O4/c12-6-10(15)13-9(11(16)17)5-7-1-3-8(14)4-2-7/h1-4,9,14H,5-6,12H2,(H,13,15)(H,16,17)/t9-/m0/s1
• InChI Key: XBGGUPMXALFZOT-VIFPVBQESA-N
• Popularity: 282 references in papers

Physical and Chemical Properties

• Molecular Formula: C₁₁H₁₄N₂O₄
• Molecular Weight: 238.24 g/mol
• Exact Mass: 238.09535693 g/mol
• Topological Polar Surface Area (TPSA): 113.00 Ų
• XlogP: -3.30

Synonyms

• 658-79-7
• Gly-Tyr
• N-Glycyl-L-tyrosine
• Glycyltyrosine
• H-Gly-Tyr-OH
• L-Tyrosine, glycyl-
• glycyl-tyrosine
• (S)-2-(2-Aminoacetamido)-3-(4-hydroxyphenyl)propanoic acid
• (2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoic acid
• Glycyl-L-tyrosine 2-hydrate
• CHEMBL53400
• CHEBI:73517
• A226496H4O
• L-Tyrosine, glycyl-, monomer
• GY dipeptide
• NSC-83260
• UNII-A226496H4O
• G-Y Dipeptide
• EINECS 211-525-1
• Gly-L-Tyr
• NSC 83260
• L-Glycyl-L-Tyrosine
• NSC 118362
• (2S)-2-(2-aminoacetamido)-3-(4-hydroxyphenyl)propanoic acid
• APPROVED Glycyltyrosine
• Glycine Tyrosine dipeptide
• Glycine-Tyrosine dipeptide
• SCHEMBL479126
• GLYCYLTYROSINE [WHO-DD]
• DTXSID701316223
• BCP24671
• GLYCYL-L-TYROSINE [USP-RS]
• GY
• BDBM50188508
• AKOS010366204
• AC-6976
• CS-W010308
• HY-W009592
• s10390
• DS-13668
• G0145
• EN300-302626
• G-6370
• Q27140599
• 2-(2-Amino-acetylamino)-3-(4-hydroxy-phenyl)-propionic acid
• (S)-2-(2-Amino-acetylamino)-3-(4-hydroxy-phenyl)-propionic acid
• G-Y
• Melanin synthesized from Gly-Tyr substrate catalyzed by tyrosinase for 22 hrs, >10 kd fraction
• Melanin synthesized from Gly-Tyr substrate catalyzed by tyrosinase for 3 hrs, HCl insoluble portion (precipitate)

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL1255126	O15151	Protein Mdm4	97.25%	90.20%
CHEMBL3060	Q9Y345	Glycine transporter 2	96.12%	99.17%
CHEMBL2581	P07339	Cathepsin D	96.00%	98.95%
CHEMBL5619	P27695	DNA-(apurinic or apyrimidinic site) lyase	92.64%	91.11%
CHEMBL4793	Q86TI2	Dipeptidyl peptidase IX	92.60%	96.95%
CHEMBL4203	Q9HAZ1	Dual specificity protein kinase CLK4	92.35%	94.45%
CHEMBL1907594	P30926	Neuronal acetylcholine receptor; alpha3/beta4	92.09%	97.23%
CHEMBL4657	Q6V1X1	Dipeptidyl peptidase VIII	91.59%	97.21%
CHEMBL3976	Q9UHL4	Dipeptidyl peptidase II	91.53%	92.29%
CHEMBL4101	P17612	cAMP-dependent protein kinase alpha-catalytic subunit	89.21%	82.86%
CHEMBL3091268	Q92753	Nuclear receptor ROR-beta	88.22%	95.50%
CHEMBL1907591	P30926	Neuronal acetylcholine receptor; alpha4/beta4	87.83%	100.00%
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	84.57%	96.09%
CHEMBL3108638	O15164	Transcription intermediary factor 1-alpha	82.87%	95.56%
CHEMBL2514	O95665	Neurotensin receptor 2	82.65%	100.00%
CHEMBL5845	P23415	Glycine receptor subunit alpha-1	82.53%	90.71%
CHEMBL1860	P10827	Thyroid hormone receptor alpha	81.46%	99.15%
CHEMBL340	P08684	Cytochrome P450 3A4	81.14%	91.19%
CHEMBL2535	P11166	Glucose transporter	80.87%	98.75%
CHEMBL3891	P07384	Calpain 1	80.23%	93.04%

Plants that contains it

There are no matching plants.

Cross-Links

• PubChem: 92829
• LOTUS: LTS0131749
• wikiData: Q27140599