Glu-Met

Details

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Internal ID 84108cc2-a474-4007-8c22-0d9fa28fbad1
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Dipeptides
IUPAC Name (4S)-4-amino-5-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-5-oxopentanoic acid
SMILES (Canonical) CSCCC(C(=O)O)NC(=O)C(CCC(=O)O)N
SMILES (Isomeric) CSCC[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)O)N
InChI InChI=1S/C10H18N2O5S/c1-18-5-4-7(10(16)17)12-9(15)6(11)2-3-8(13)14/h6-7H,2-5,11H2,1H3,(H,12,15)(H,13,14)(H,16,17)/t6-,7-/m0/s1
InChI Key SXGAGTVDWKQYCX-BQBZGAKWSA-N
Popularity 7 references in papers

Physical and Chemical Properties

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Molecular Formula C10H18N2O5S
Molecular Weight 278.33 g/mol
Exact Mass 278.09364285 g/mol
Topological Polar Surface Area (TPSA) 155.00 Ų
XlogP -3.70

Synonyms

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H-GLU(MET)-OH
4423-22-7
H-Glu-Met-OH
glutamyl-methionine
L-Glutamyl-L-Methionine
L-alpha-glutamyl-L-methionine
Glutamylmethionine
(4S)-4-amino-5-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-5-oxopentanoic acid
EM dipeptide
E-M Dipeptide
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Glu-Met

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4040 P28482 MAP kinase ERK2 99.33% 83.82%
CHEMBL221 P23219 Cyclooxygenase-1 96.36% 90.17%
CHEMBL2581 P07339 Cathepsin D 96.07% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.49% 96.09%
CHEMBL236 P41143 Delta opioid receptor 95.36% 99.35%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 94.75% 92.29%
CHEMBL3359 P21462 Formyl peptide receptor 1 94.46% 93.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 93.55% 99.17%
CHEMBL1255126 O15151 Protein Mdm4 91.61% 90.20%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 87.84% 100.00%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 85.95% 98.33%
CHEMBL340 P08684 Cytochrome P450 3A4 85.84% 91.19%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 85.69% 97.21%
CHEMBL2514 O95665 Neurotensin receptor 2 85.04% 100.00%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 84.34% 96.95%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 84.05% 96.00%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 82.60% 93.10%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 82.53% 96.03%
CHEMBL3784 Q09472 Histone acetyltransferase p300 82.32% 93.33%
CHEMBL2413 P32246 C-C chemokine receptor type 1 81.60% 89.50%
CHEMBL3776 Q14790 Caspase-8 81.54% 97.06%
CHEMBL3308 P55212 Caspase-6 80.47% 97.56%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 80.36% 94.33%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 80.32% 98.24%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 6426949
LOTUS LTS0137401
wikiData Q27140587