(1R,3aR,5aR,6R,9aS)-Dodecahydro-6-(2Z)-2-penten-4-ynylpyrrolo(1,2-a)quinoline-1-ethanol

Details

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Internal ID a444a6b0-4b67-4c65-9ea7-35f478a043d0
Taxonomy Alkaloids and derivatives > Histrionicotoxins
IUPAC Name 2-[(1R,3aR,5aR,6R,9aS)-6-[(Z)-pent-2-en-4-ynyl]-1,2,3,3a,4,5,5a,6,7,8,9,9a-dodecahydropyrrolo[1,2-a]quinolin-1-yl]ethanol
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C19H29NO/c1-2-3-4-6-15-7-5-8-19-18(15)12-11-16-9-10-17(13-14-21)20(16)19/h1,3-4,15-19,21H,5-14H2/b4-3-/t15-,16-,17+,18+,19-/m0/s1
InChI Key IQTIQAXNJBRKRG-IZDLKJCPSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C19H29NO
Molecular Weight 287.40 g/mol
Exact Mass 287.224914549 g/mol
Topological Polar Surface Area (TPSA) 23.50 Ų
XlogP 3.90

Synonyms

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Histrionicotoxin D
HTX D
55893-12-4
01N796R81A
DTXSID401029722
2-[(1R,3aR,5aR,6R,9aS)-6-[(Z)-pent-2-en-4-ynyl]-1,2,3,3a,4,5,5a,6,7,8,9,9a-dodecahydropyrrolo[1,2-a]quinolin-1-yl]ethanol
Pyrrolo(1,2-a)quinoline-1-ethanol, dodecahydro-6-(2Z)-2-penten-4-ynyl-, (1R,3aR,5aR,6R,9aS)-
(1R,3aR,5aR,6R,9aS)-Dodecahydro-6-(2Z)-2-penten-4-ynylpyrrolo[1,2-a]quinoline-1-ethanol
(1R,3AR,5AR,6R,9AS)-DODECAHYDRO-6-(2Z)-2-PENTEN-4-YNYLPYRROLO(1,2-A)QUINOLINE-1-ETHANOL
Pyrrolo(1,2-a)quinoline-1-ethanol, dodecahydro-6-(2-penten-4-ynyl)-, (1R-(1alpha,3abeta,5aalpha,6alpha(Z),9aalpha))-
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of (1R,3aR,5aR,6R,9aS)-Dodecahydro-6-(2Z)-2-penten-4-ynylpyrrolo(1,2-a)quinoline-1-ethanol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL230 P35354 Cyclooxygenase-2 94.66% 89.63%
CHEMBL238 Q01959 Dopamine transporter 90.55% 95.88%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.55% 97.25%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.81% 97.09%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 86.37% 94.78%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 85.98% 95.50%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 85.84% 96.09%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 83.06% 100.00%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 82.87% 86.92%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.90% 95.89%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 81.18% 93.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 80.80% 93.99%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 80.68% 92.62%
CHEMBL2581 P07339 Cathepsin D 80.40% 98.95%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 6437870
LOTUS LTS0135407
wikiData Q5548689