Ganefromycin beta

Details

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Internal ID 6853d87a-0771-445f-b0b9-8997e07d75e0
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbohydrates and carbohydrate conjugates > Oligosaccharides
IUPAC Name (2E,4E,6E)-7-[5-[(4E,6E)-8-[[(2S)-2-[(2S,4S,6S)-2,4-dihydroxy-5,5-dimethyl-6-[(1E,3Z)-penta-1,3-dienyl]oxan-2-yl]-3-[(2R,4S,5R,6S)-5-[(2R,4R,5S,6S)-5-[(2S,4S,5R,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxypropanoyl]amino]-3-methoxy-4-methylocta-4,6-dien-2-yl]-3-hydroxyoxolan-2-yl]hepta-2,4,6-trienoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C57H89NO19/c1-13-14-17-24-46-56(7,8)45(60)31-57(65,77-46)38(55(64)58-26-21-20-22-33(2)52(69-12)34(3)41-27-39(59)40(74-41)23-18-15-16-19-25-47(61)62)32-70-48-29-43(67-10)53(36(5)72-48)76-50-30-44(68-11)54(37(6)73-50)75-49-28-42(66-9)51(63)35(4)71-49/h13-25,34-46,48-54,59-60,63,65H,26-32H2,1-12H3,(H,58,64)(H,61,62)/b14-13-,16-15+,21-20+,23-18+,24-17+,25-19+,33-22+/t34?,35-,36-,37-,38+,39?,40?,41?,42-,43-,44+,45-,46-,48+,49-,50+,51+,52?,53+,54-,57-/m0/s1
InChI Key GYALAKIKPRXBBB-XRFFAWBTSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C57H89NO19
Molecular Weight 1092.30 g/mol
Exact Mass 1091.60287961 g/mol
Topological Polar Surface Area (TPSA) 258.00 Ų
XlogP 4.90

Synonyms

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CHEMBL445828

2D Structure

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2D Structure of Ganefromycin beta

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.49% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.04% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.57% 85.14%
CHEMBL226 P30542 Adenosine A1 receptor 94.39% 95.93%
CHEMBL2815 P04629 Nerve growth factor receptor Trk-A 91.86% 87.16%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.26% 95.89%
CHEMBL340 P08684 Cytochrome P450 3A4 90.65% 91.19%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 90.34% 95.71%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 90.16% 97.21%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 89.99% 96.95%
CHEMBL1914 P06276 Butyrylcholinesterase 89.49% 95.00%
CHEMBL221 P23219 Cyclooxygenase-1 89.16% 90.17%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 88.47% 96.38%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.16% 89.00%
CHEMBL5678 P34947 G protein-coupled receptor kinase 5 87.96% 88.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 87.50% 95.50%
CHEMBL6136 O60341 Lysine-specific histone demethylase 1 86.89% 95.58%
CHEMBL251 P29274 Adenosine A2a receptor 86.65% 94.40%
CHEMBL2413 P32246 C-C chemokine receptor type 1 85.83% 89.50%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 85.67% 91.07%
CHEMBL5028 O14672 ADAM10 85.05% 97.50%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 85.03% 96.25%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 84.99% 94.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.69% 95.89%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.55% 96.77%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 84.07% 91.03%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.86% 94.45%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.75% 99.23%
CHEMBL255 P29275 Adenosine A2b receptor 83.51% 98.59%
CHEMBL2716 Q8WUI4 Histone deacetylase 7 82.47% 89.44%
CHEMBL3837 P07711 Cathepsin L 82.35% 96.61%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 82.16% 96.00%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 82.12% 92.29%
CHEMBL3437 Q16853 Amine oxidase, copper containing 82.11% 94.00%
CHEMBL2179 P04062 Beta-glucocerebrosidase 81.82% 85.31%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.71% 99.17%
CHEMBL2534 O15530 3-phosphoinositide dependent protein kinase-1 81.43% 95.36%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 81.10% 91.24%
CHEMBL5255 O00206 Toll-like receptor 4 80.83% 92.50%
CHEMBL1163125 O60885 Bromodomain-containing protein 4 80.51% 97.31%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 80.38% 95.83%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.33% 93.56%
CHEMBL1075317 P61964 WD repeat-containing protein 5 80.20% 96.33%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10558105
LOTUS LTS0081335
wikiData Q77371416