Furo(2,3-b)quinolin-4(2H)-one, 3,9-dihydro-2-(1-hydroxy-1-methylethyl)-8-methoxy-9-methyl-

Details

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Internal ID ed560cd7-0e40-404c-9a46-13dd7a3c270a
Taxonomy Organoheterocyclic compounds > Quinolines and derivatives > Dihydrofuranoquinolines
IUPAC Name 2-(2-hydroxypropan-2-yl)-8-methoxy-9-methyl-2,3-dihydrofuro[2,3-b]quinolin-4-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C16H19NO4/c1-16(2,19)12-8-10-14(18)9-6-5-7-11(20-4)13(9)17(3)15(10)21-12/h5-7,12,19H,8H2,1-4H3
InChI Key VPNKCPHNFBSHAP-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C16H19NO4
Molecular Weight 289.33 g/mol
Exact Mass 289.13140809 g/mol
Topological Polar Surface Area (TPSA) 59.00 Ų
XlogP 1.90

Synonyms

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2-(2-Hydroxypropan-2-yl)-8-methoxy-9-methyl-2,3-dihydrofuro[2,3-b]quinolin-4(9H)-one
3921-70-8
Furo(2,3-b)quinolin-4(9H)-one, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-8-methoxy-9-methyl-
3,9-Dihydro-2-(1-hydroxy-1-methylethyl)-8-methoxy-9-methylfuro(2,3-b)quinolin-4(2H)-one
Furo(2,3-b)quinolin-4(2H)-one, 3,9-dihydro-2-(1-hydroxy-1-methylethyl)-8-methoxy-9-methyl-
DTXSID70963754
VPNKCPHNFBSHAP-UHFFFAOYSA-N
2-(2-hydroxypropan-2-yl)-8-methoxy-9-methyl-3,9-dihydrofuro[2,3-b]quinolin-4(2H)-one
2-(1-Hydroxy-1-methylethyl)-8-methoxy-9-methyl-3,9-dihydrofuro[2,3-b]quinolin-4(2H)-one #

2D Structure

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2D Structure of Furo(2,3-b)quinolin-4(2H)-one, 3,9-dihydro-2-(1-hydroxy-1-methylethyl)-8-methoxy-9-methyl-

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.45% 95.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.95% 85.14%
CHEMBL2581 P07339 Cathepsin D 95.94% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.97% 96.09%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 93.57% 94.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.09% 86.33%
CHEMBL2535 P11166 Glucose transporter 92.24% 98.75%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.99% 95.89%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.52% 97.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.32% 91.11%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 87.88% 92.62%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.56% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.54% 89.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 86.86% 97.14%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 86.68% 100.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 83.91% 93.99%
CHEMBL217 P14416 Dopamine D2 receptor 83.71% 95.62%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 80.74% 89.62%
CHEMBL2056 P21728 Dopamine D1 receptor 80.11% 91.00%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 80.04% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Balfourodendron riedelianum

Cross-Links

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PubChem 206269
LOTUS LTS0204701
wikiData Q82945669