Friulimicin C

Details

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Internal ID 19fadc54-c1be-4d39-b999-b8bf4256ea4c
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Oligopeptides
IUPAC Name 2-[16-(1-aminoethyl)-3-[[4-amino-2-[[(E)-10-methyldodec-3-enoyl]amino]-4-oxobutanoyl]amino]-22,28-bis(carboxymethyl)-4-methyl-2,6,12,15,18,21,24,27,30,33-decaoxo-13-propan-2-yl-1,5,11,14,17,20,23,26,29,32-decazatricyclo[32.4.0.07,11]octatriacontan-31-yl]propanoic acid
SMILES (Canonical) CCC(C)CCCCCC=CCC(=O)NC(CC(=O)N)C(=O)NC1C(NC(=O)C2CCCN2C(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C3CCCCN3C1=O)C(C)C(=O)O)CC(=O)O)CC(=O)O)C(C)N)C(C)C)C
SMILES (Isomeric) CCC(C)CCCCC/C=C/CC(=O)NC(CC(=O)N)C(=O)NC1C(NC(=O)C2CCCN2C(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C3CCCCN3C1=O)C(C)C(=O)O)CC(=O)O)CC(=O)O)C(C)N)C(C)C)C
InChI InChI=1S/C58H92N14O19/c1-8-30(4)18-13-11-9-10-12-14-21-40(74)64-34(24-39(60)73)51(83)70-48-33(7)63-52(84)38-20-17-23-72(38)56(88)45(29(2)3)68-55(87)47(32(6)59)67-42(76)28-62-49(81)35(25-43(77)78)65-41(75)27-61-50(82)36(26-44(79)80)66-54(86)46(31(5)58(90)91)69-53(85)37-19-15-16-22-71(37)57(48)89/h12,14,29-38,45-48H,8-11,13,15-28,59H2,1-7H3,(H2,60,73)(H,61,82)(H,62,81)(H,63,84)(H,64,74)(H,65,75)(H,66,86)(H,67,76)(H,68,87)(H,69,85)(H,70,83)(H,77,78)(H,79,80)(H,90,91)/b14-12+
InChI Key MDBSKEKVSGDWLT-WYMLVPIESA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C58H92N14O19
Molecular Weight 1289.40 g/mol
Exact Mass 1288.66631676 g/mol
Topological Polar Surface Area (TPSA) 513.00 Ų
XlogP -3.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Friulimicin C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.79% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.48% 96.09%
CHEMBL236 P41143 Delta opioid receptor 98.27% 99.35%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.90% 91.11%
CHEMBL4801 P29466 Caspase-1 97.88% 96.85%
CHEMBL226 P30542 Adenosine A1 receptor 97.43% 95.93%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 97.09% 93.00%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 96.54% 91.03%
CHEMBL221 P23219 Cyclooxygenase-1 95.96% 90.17%
CHEMBL3060 Q9Y345 Glycine transporter 2 95.10% 99.17%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 94.99% 96.11%
CHEMBL4588 P22894 Matrix metalloproteinase 8 94.52% 94.66%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 94.26% 82.38%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 93.17% 90.71%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 93.11% 95.50%
CHEMBL5103 Q969S8 Histone deacetylase 10 93.07% 90.08%
CHEMBL4071 P08311 Cathepsin G 92.92% 94.64%
CHEMBL5203 P33316 dUTP pyrophosphatase 92.24% 99.18%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 91.46% 98.33%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 91.40% 89.34%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 91.21% 98.24%
CHEMBL3524 P56524 Histone deacetylase 4 91.19% 92.97%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.94% 95.89%
CHEMBL1902 P62942 FK506-binding protein 1A 90.40% 97.05%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.55% 93.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.10% 94.45%
CHEMBL2413 P32246 C-C chemokine receptor type 1 88.90% 89.50%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 88.50% 93.03%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 88.30% 96.90%
CHEMBL2443 P49862 Kallikrein 7 88.19% 94.00%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 87.31% 96.00%
CHEMBL220 P22303 Acetylcholinesterase 86.89% 94.45%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 86.58% 96.03%
CHEMBL2514 O95665 Neurotensin receptor 2 86.51% 100.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.93% 97.09%
CHEMBL4462 Q8IXJ6 NAD-dependent deacetylase sirtuin 2 85.75% 90.24%
CHEMBL333 P08253 Matrix metalloproteinase-2 85.52% 96.31%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 85.41% 96.47%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 84.79% 96.38%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 84.65% 97.64%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 84.33% 90.24%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.88% 89.00%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 83.30% 98.94%
CHEMBL2094135 Q96BI3 Gamma-secretase 82.58% 98.05%
CHEMBL340 P08684 Cytochrome P450 3A4 82.45% 91.19%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.62% 94.33%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 81.55% 100.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 81.43% 95.56%
CHEMBL1781 P11387 DNA topoisomerase I 81.15% 97.00%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 80.40% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139585781
LOTUS LTS0123868
wikiData Q77491533