Formicamycin M

Details

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Internal ID fd01edac-321e-4c2e-b19f-e2ed37ec3d61
Taxonomy Benzenoids > Tetralins
IUPAC Name (5aR,11aR)-10-bromo-7-(2,4-dimethoxy-6-methylphenyl)-2,4,5a-trihydroxy-9-methoxy-12,12-dimethyl-11,11a-dihydrotetracene-5,6-dione
SMILES (Canonical) CC1=CC(=CC(=C1C2=CC(=C(C3=C2C(=O)C4(C(C3)C(C5=C(C4=O)C(=CC(=C5)O)O)(C)C)O)Br)OC)OC)OC
SMILES (Isomeric) CC1=CC(=CC(=C1C2=CC(=C(C3=C2C(=O)[C@@]4([C@H](C3)C(C5=C(C4=O)C(=CC(=C5)O)O)(C)C)O)Br)OC)OC)OC
InChI InChI=1S/C30H29BrO8/c1-13-7-15(37-4)10-20(38-5)23(13)16-11-21(39-6)26(31)17-12-22-29(2,3)18-8-14(32)9-19(33)25(18)28(35)30(22,36)27(34)24(16)17/h7-11,22,32-33,36H,12H2,1-6H3/t22-,30-/m1/s1
InChI Key KHXIDNHTRXJJNS-YKGWIAGDSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C30H29BrO8
Molecular Weight 597.40 g/mol
Exact Mass 596.10458 g/mol
Topological Polar Surface Area (TPSA) 123.00 Ų
XlogP 6.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Formicamycin M

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.28% 91.11%
CHEMBL3192 Q9BY41 Histone deacetylase 8 97.79% 93.99%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 96.26% 99.15%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.06% 95.56%
CHEMBL4208 P20618 Proteasome component C5 96.03% 90.00%
CHEMBL1937 Q92769 Histone deacetylase 2 95.79% 94.75%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.81% 96.09%
CHEMBL241 Q14432 Phosphodiesterase 3A 93.47% 92.94%
CHEMBL2535 P11166 Glucose transporter 92.82% 98.75%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.08% 97.09%
CHEMBL1929 P47989 Xanthine dehydrogenase 91.19% 96.12%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.76% 86.33%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 89.97% 93.40%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.89% 94.00%
CHEMBL2581 P07339 Cathepsin D 89.35% 98.95%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 89.18% 91.07%
CHEMBL1907 P15144 Aminopeptidase N 88.70% 93.31%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.47% 95.89%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.16% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.49% 89.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.60% 94.45%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.60% 97.14%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 81.13% 92.68%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 80.87% 91.79%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 80.60% 82.38%
CHEMBL340 P08684 Cytochrome P450 3A4 80.55% 91.19%
CHEMBL2056 P21728 Dopamine D1 receptor 80.24% 91.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146684593
LOTUS LTS0197336
wikiData Q105141364