Formicamycin H

Details

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Internal ID 84dd4ef4-8830-4c02-988f-ef7c4758b290
Taxonomy Benzenoids > Tetralins
IUPAC Name (5aR,11aR)-1,3-dichloro-7-(3-chloro-4,6-dimethoxy-2-methylphenyl)-2,4,5a-trihydroxy-9-methoxy-12,12-dimethyl-11,11a-dihydrotetracene-5,6-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H27Cl3O8/c1-11-18(15(40-5)10-16(41-6)22(11)31)14-9-13(39-4)7-12-8-17-29(2,3)21-20(25(34)24(33)26(35)23(21)32)28(37)30(17,38)27(36)19(12)14/h7,9-10,17,34-35,38H,8H2,1-6H3/t17-,30-/m1/s1
InChI Key WITUCWDZFNOOOS-BJLXPSRBSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C30H27Cl3O8
Molecular Weight 621.90 g/mol
Exact Mass 620.077151 g/mol
Topological Polar Surface Area (TPSA) 123.00 Ų
XlogP 7.40

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Formicamycin H

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.79% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.13% 95.56%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 93.47% 96.00%
CHEMBL2581 P07339 Cathepsin D 93.28% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.20% 94.45%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.78% 86.33%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 91.62% 92.68%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.09% 94.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.87% 96.09%
CHEMBL2056 P21728 Dopamine D1 receptor 90.69% 91.00%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 89.90% 91.03%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.61% 95.89%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 88.71% 99.15%
CHEMBL3192 Q9BY41 Histone deacetylase 8 86.06% 93.99%
CHEMBL2337 P48067 Glycine transporter 1 84.89% 95.45%
CHEMBL2146302 O94925 Glutaminase kidney isoform, mitochondrial 84.50% 100.00%
CHEMBL4805 Q99572 P2X purinoceptor 7 84.35% 97.50%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.98% 93.03%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 83.70% 96.95%
CHEMBL217 P14416 Dopamine D2 receptor 83.54% 95.62%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 83.25% 96.67%
CHEMBL241 Q14432 Phosphodiesterase 3A 83.16% 92.94%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.15% 97.09%
CHEMBL340 P08684 Cytochrome P450 3A4 83.07% 91.19%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.70% 97.14%
CHEMBL1966 Q02127 Dihydroorotate dehydrogenase 82.50% 96.09%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 82.20% 96.21%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 82.14% 100.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.37% 89.00%
CHEMBL4247 Q9UM73 ALK tyrosine kinase receptor 81.23% 96.86%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 81.13% 96.38%
CHEMBL4208 P20618 Proteasome component C5 80.93% 90.00%
CHEMBL4306 P22460 Voltage-gated potassium channel subunit Kv1.5 80.80% 94.03%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 80.60% 95.34%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.09% 91.07%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146684588
LOTUS LTS0035172
wikiData Q105306515