Formicamycin C

Details

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Internal ID b21213ce-563d-4719-a5c0-80cdbd07d733
Taxonomy Benzenoids > Tetralins
IUPAC Name (5aR,11aR)-1,10-dichloro-7-(2,4-dimethoxy-6-methylphenyl)-2,4,5a-trihydroxy-9-methoxy-12,12-dimethyl-11,11a-dihydrotetracene-5,6-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H28Cl2O8/c1-12-7-13(38-4)8-18(39-5)21(12)14-9-19(40-6)25(31)15-10-20-29(2,3)24-23(16(33)11-17(34)26(24)32)28(36)30(20,37)27(35)22(14)15/h7-9,11,20,33-34,37H,10H2,1-6H3/t20-,30-/m1/s1
InChI Key BDNWOBBVDVIJGL-PRAQEBQASA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C30H28Cl2O8
Molecular Weight 587.40 g/mol
Exact Mass 586.1161232 g/mol
Topological Polar Surface Area (TPSA) 123.00 Ų
XlogP 6.80

Synonyms

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CHEMBL4646535

2D Structure

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2D Structure of Formicamycin C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.33% 91.11%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 95.90% 99.15%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.64% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.40% 86.33%
CHEMBL4040 P28482 MAP kinase ERK2 92.32% 83.82%
CHEMBL3192 Q9BY41 Histone deacetylase 8 92.25% 93.99%
CHEMBL1937 Q92769 Histone deacetylase 2 91.55% 94.75%
CHEMBL2535 P11166 Glucose transporter 91.42% 98.75%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.24% 97.09%
CHEMBL2581 P07339 Cathepsin D 91.22% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.00% 96.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.89% 95.89%
CHEMBL2056 P21728 Dopamine D1 receptor 89.79% 91.00%
CHEMBL4208 P20618 Proteasome component C5 89.69% 90.00%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 89.52% 96.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 88.80% 94.45%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 87.09% 96.77%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.06% 94.00%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 86.65% 93.40%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 86.49% 91.07%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 86.43% 96.95%
CHEMBL241 Q14432 Phosphodiesterase 3A 86.02% 92.94%
CHEMBL2337 P48067 Glycine transporter 1 84.11% 95.45%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.40% 97.14%
CHEMBL1907 P15144 Aminopeptidase N 83.03% 93.31%
CHEMBL4805 Q99572 P2X purinoceptor 7 82.69% 97.50%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 82.55% 92.68%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.34% 92.62%
CHEMBL340 P08684 Cytochrome P450 3A4 82.28% 91.19%
CHEMBL3492 P49721 Proteasome Macropain subunit 81.89% 90.24%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 81.88% 100.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 81.55% 85.14%
CHEMBL3180 O00748 Carboxylesterase 2 81.10% 90.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.42% 93.03%
CHEMBL4145 Q9UKV0 Histone deacetylase 9 80.24% 85.49%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.00% 89.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146684583
LOTUS LTS0212651
wikiData Q104924482