Flustramine L

Details

Top
Internal ID 573fd443-19bc-416d-9af4-c1de77cf1747
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Pyrroloindoles
IUPAC Name (3aS,8bS)-5-bromo-3-methyl-7,8b-bis(3-methylbut-2-enyl)-1,2,3a,4-tetrahydropyrrolo[2,3-b]indol-8-ol
SMILES (Canonical) CC(=CCC1=CC(=C2C(=C1O)C3(CCN(C3N2)C)CC=C(C)C)Br)C
SMILES (Isomeric) CC(=CCC1=CC(=C2C(=C1O)[C@@]3(CCN([C@@H]3N2)C)CC=C(C)C)Br)C
InChI InChI=1S/C21H29BrN2O/c1-13(2)6-7-15-12-16(22)18-17(19(15)25)21(9-8-14(3)4)10-11-24(5)20(21)23-18/h6,8,12,20,23,25H,7,9-11H2,1-5H3/t20-,21-/m0/s1
InChI Key HFPWSDSFBVKNTG-SFTDATJTSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

Top
Molecular Formula C21H29BrN2O
Molecular Weight 405.40 g/mol
Exact Mass 404.14633 g/mol
Topological Polar Surface Area (TPSA) 35.50 Ų
XlogP 6.30

Synonyms

Top
CHEMBL1078479

2D Structure

Top
2D Structure of Flustramine L

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL240 Q12809 HERG 98.30% 89.76%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.78% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.14% 91.11%
CHEMBL2581 P07339 Cathepsin D 96.21% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.86% 94.45%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 93.47% 93.40%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.23% 95.89%
CHEMBL1937 Q92769 Histone deacetylase 2 90.00% 94.75%
CHEMBL3192 Q9BY41 Histone deacetylase 8 89.83% 93.99%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.45% 97.25%
CHEMBL241 Q14432 Phosphodiesterase 3A 86.12% 92.94%
CHEMBL1994 P08235 Mineralocorticoid receptor 86.03% 100.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.25% 97.09%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 85.09% 89.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 84.97% 95.56%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 84.94% 91.03%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 84.65% 82.38%
CHEMBL4072 P07858 Cathepsin B 84.35% 93.67%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 84.10% 97.50%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 84.04% 85.14%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 83.57% 93.04%
CHEMBL344 Q99705 Melanin-concentrating hormone receptor 1 83.10% 92.50%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 80.87% 96.39%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 80.84% 95.50%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 80.72% 94.00%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 44557717
LOTUS LTS0070567
wikiData Q105027449