Majusculamide C

Details

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Internal ID dac11493-14fc-4081-b9c8-29df6308e630
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (2S,8S,14S,17S,20S,25S,28R,29S)-2,8-bis[(2S)-butan-2-yl]-28-ethyl-17-[(4-methoxyphenyl)methyl]-7,13,16,20,22,22,25,29-octamethyl-14-propan-2-yl-1-oxa-4,7,10,13,16,19,24,27-octazacyclotriacontane-3,6,9,12,15,18,21,23,26,30-decone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C50H80N8O12/c1-17-28(6)40-45(64)51-25-37(59)57(14)39(27(4)5)47(66)56(13)36(24-33-20-22-34(69-16)23-21-33)44(63)53-31(9)42(61)50(11,12)49(68)54-32(10)43(62)55-35(19-3)30(8)48(67)70-41(29(7)18-2)46(65)52-26-38(60)58(40)15/h20-23,27-32,35-36,39-41H,17-19,24-26H2,1-16H3,(H,51,64)(H,52,65)(H,53,63)(H,54,68)(H,55,62)/t28-,29-,30-,31-,32-,35+,36-,39-,40-,41-/m0/s1
InChI Key KDZUJZSBNBCYEK-URQIXXPJSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C50H80N8O12
Molecular Weight 985.20 g/mol
Exact Mass 984.58957002 g/mol
Topological Polar Surface Area (TPSA) 259.00 Ų
XlogP 5.10

Synonyms

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74CZ7Q2FQQ
83712-17-8
Cyclo(L-alanyl-(2S,3R)-3-amino-2-methylpentanoyl-(2S,3S)-2-hydroxy-3-methylpentanoylglycyl-N-methyl-L-isoleucylglycyl-N-methyl-L-valyl-N,O-dimethyl-L-tyrosyl-(4S)-4-amino-2,2-dimethyl-3-oxopentanoyl)
DTXSID801335644
RefChem:925208
DTXCID001765437
2,8-di(butan-2-yl)-28-ethyl-17-((4-methoxyphenyl)methyl)-7,13,16,20,22,22,25,29-octamethyl-14-propan-2-yl-1-oxa-4,7,10,13,16,19,24,27-octazacyclotriacontane-3,6,9,12,15,18,21,23,26,30-decone
(2S,8S,14S,17S,20S,25S)-2,8-bis((2S)-butan-2-yl)-28-ethyl-17-((4-methoxyphenyl)methyl)-7,13,16,20,22,22,25,29-octamethyl-14-propan-2-yl-1-oxa-4,7,10,13,16,19,24,27-octazacyclotriacontane-3,6,9,12,15,18,21,23,26,30-decone
(8S,14S,17S,25S,28R,29S)-2-((2S)-butan-2-yl)-28-ethyl-17-((4-methoxyphenyl)methyl)-7,13,16,20,22,22,25,29-octamethyl-8-(3-methylbutan-2-yl)-14-propan-2-yl-1-oxa-4,7,10,13,16,19,24,27-octazacyclotriacontane-3,6,9,12,15,18,21,23,26,30-decone
UNII-74CZ7Q2FQQ
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Majusculamide C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.35% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.91% 97.25%
CHEMBL2581 P07339 Cathepsin D 98.14% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.12% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 95.60% 85.14%
CHEMBL255 P29275 Adenosine A2b receptor 95.34% 98.59%
CHEMBL4208 P20618 Proteasome component C5 95.00% 90.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 93.88% 93.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.96% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.95% 95.56%
CHEMBL3492 P49721 Proteasome Macropain subunit 92.49% 90.24%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.81% 95.89%
CHEMBL221 P23219 Cyclooxygenase-1 91.76% 90.17%
CHEMBL6175 Q9H3R0 Lysine-specific demethylase 4C 91.31% 96.69%
CHEMBL4588 P22894 Matrix metalloproteinase 8 91.00% 94.66%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.74% 94.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.85% 97.09%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 88.02% 92.68%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.32% 86.33%
CHEMBL5103 Q969S8 Histone deacetylase 10 86.02% 90.08%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 85.86% 91.03%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 83.39% 91.07%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.20% 97.14%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 82.56% 96.00%
CHEMBL4616 Q92847 Ghrelin receptor 82.27% 92.00%
CHEMBL1949 P62937 Cyclophilin A 82.21% 98.57%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 82.02% 90.71%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 81.88% 96.77%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 81.56% 92.88%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 81.40% 100.00%
CHEMBL333 P08253 Matrix metalloproteinase-2 80.64% 96.31%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 44584099
LOTUS LTS0085108
wikiData Q105139834